點用阿托品控制近視之臺灣國小學童配戴漸進多焦點鏡片其視覺功能與度數變化之追蹤調查

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点用阿托品控制近视之台湾国小学童配戴渐进多焦点镜片其视觉功能与度数变化之追踪调查

A Follow-up Study of Visual Functions Improvement and Refractive Development in Taiwanese Myopic Children with Atropine

粘瑛珊 , 硕士　　导师：郭蕙瑛　　

繁体中文

阿托品；近视控制；渐进多焦点镜片；视觉功能；近视学童； Atropine ； Myopia control ； progressive addition lenses ； visual functions ； Myopic Children

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摘要 │ 参考文献 (33) │ 国际计量

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Purpose: To investigate the improvement of visual functions and the effect of myopia control in Taiwanese myopic schoolchildren with the combination of Atropine usage and progressive addition lenses. The effect of the types of addition prescriptions (Uniform or Customized) on slowing down myopia progression is also studied.
Methods: Subjects were 40 myopic schoolchildren aged between 8~12 years and have spherical equivalents between -0.25 ~ -5.50D. All of the subjects are currently using Atropine to control myopia and they were randomized to wear the uniform or customized progression addition lenses for one-year follow-up. The differences in visual functions and myopia control effect were compared. 
Results: The mean binocular distant visual acuity of all the subjects were 0.41 logMAR in the original status, and improved to 0.07logMAR after applying distance correction prescriptions(p<.0001). For near visual acuities, the mean binocular high contrast NVA were 0.14 logMARin the original status, and improved to 0.08 logMAR with addition prescriptions(p<.0001); the low contrast NVA enhanced from 0.29 to 0.23 logMAR(p<.0001).In the aspect of myopia control, there is no significant difference in annual myopia progression between the customized(0.24D) and the uniform(0.20D) groups.However, the mean myopia progression rate in the first year of the subjects with Atropine + PAL increased only 0.21D comparing to the control group(0.66D) (p<.0001).
Conclusion: The myopia control effect is significantly better with the combination of Atropine + PAL (up to 70%), and the visual function is also significantly improved.

参考文献 ( 33 ) 〈TOP〉

Aller, T. A. (2014). Clinical management of progressive myopia. Eye (Lond), 28(2), 147-153. doi: 10.1038/eye.2013.259
连结：
Berntsen, D. A., Barr, C. D., Mutti, D. O., & Zadnik, K. (2013). Peripheral defocus and myopia progression in myopic children randomly assigned to wear single vision and progressive addition lenses. Investigative ophthalmology & visual science, 54(8), 5761.
连结：
Berntsen, D. A., Sinnott, L. T., Mutti, D. O., & Zadnik, K. (2012). A randomized trial using progressive addition lenses to evaluate theories of myopia progression in children with a high lag of accommodation. Invest Ophthalmol Vis Sci, 53(2), 640-649. doi: 10.1167/iovs.11-7769
连结：
Cheng, D., Schmid, K. L., & Woo, G. C. (2008). The effect of positive‐lens addition and base‐in prism on accommodation accuracy and near horizontal phoria in Chinese myopic children. Ophthalmic and Physiological Optics, 28(3), 225-237.
连结：
Cheng, D., Woo, G. C., Drobe, B., & Schmid, K. L. (2014). Effect of bifocal and prismatic bifocal spectacles on myopia progression in children: three-year results of a randomized clinical trial. JAMA Ophthalmol, 132(3), 258-264. doi: 10.1001/jamaophthalmol.2013.7623
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使用DOI作为永久连结

引用含有DOI的文献

DOI可强化引用精确性、增强学术圈连结，并给予使用者跨平台的良好使用经验，目前在全世界已有超过五千万个对象申请DOI。 如想对DOI的使用与概念有进一步了解，请参考 （ ） 。

DOI可强化引用精确性、增强学术圈连结，并给予使用者跨平台的良好使用经验，目前在全世界已有超过五千万个对象申请DOI。如想对DOI的使用与概念有进一步了解，请参考（）。