探討HIV感染者之憂鬱症狀及其相關因素

Depressive Symptoms in People Living with HIV: Related Factors

10.6224/JN.59.2.39

葉美伶(Mei-Ling Yeh)；徐淑婷(Su-Ting Hsu)；柯文謙(Wen-Chien Ko)；柯乃熒(Nai-Ying Ko)

人類免疫缺乏病毒 ； 憂鬱 ； 壓力知覺感受 ； 社會污名化 ； human immunodeficiency virus ； depression ； perceived stress ； social stigma

護理雜誌

59卷2期（2012 / 04 / 01）

40 - 50

繁體中文

Background: People living with HIV (human immunodeficiency virus) are at a high risk of depressive symptoms attributed to disease progression and HIV-related stress. While depressive symptoms are difficult to detect, in HIV patients they may negatively impact upon quality of life, decrease adherence to antiretroviral therapies, and further exacerbate disease progression.Purpose: Study purposes were to: (1) explore relationships among immune function indicators, perceived stress, social stigma and depressive symptoms and (2) identify depressive symptom indicators in HIV patients.Methods: Researchers recruited a total of 160 participants from infectious disease outpatient clinics at a university hospital in southern Taiwan. Chart reviews and four self-administered questionnaires (Beck Depression Inventory-Ⅱ (BDI-Ⅱ), Perceived Stress Scale, Multidimensional Scale of Perceived Social Support, and Social Impact Scale) were used to collect data.Results: Symptoms of depression (BDI ≥ 14) were observed in 68 (42.5%) patients and symptoms of major depression (BDI ≥ 29) in 25 (15.6%). We found immune function indicators negatively associated with depressive symptoms (p ＜ .05) and perceived stress and social stigma positively associated with depressive symptoms (p ＜ .01). Stepwise multiple regression analysis indicated that perceived stress and social stigma accounted for 44.4% of depressive symptom variance.Conclusion: Findings suggest that reducing perceived stress and social stigma may positively affect perceived depressive symptoms in this population and may be referenced in future development of related interventions.

Background: People living with HIV (human immunodeficiency virus) are at a high risk of depressive symptoms attributed to disease progression and HIV-related stress. While depressive symptoms are difficult to detect, in HIV patients they may negatively impact upon quality of life, decrease adherence to antiretroviral therapies, and further exacerbate disease progression.Purpose: Study purposes were to: (1) explore relationships among immune function indicators, perceived stress, social stigma and depressive symptoms and (2) identify depressive symptom indicators in HIV patients.Methods: Researchers recruited a total of 160 participants from infectious disease outpatient clinics at a university hospital in southern Taiwan. Chart reviews and four self-administered questionnaires (Beck Depression Inventory-Ⅱ (BDI-Ⅱ), Perceived Stress Scale, Multidimensional Scale of Perceived Social Support, and Social Impact Scale) were used to collect data.Results: Symptoms of depression (BDI ≥ 14) were observed in 68 (42.5%) patients and symptoms of major depression (BDI ≥ 29) in 25 (15.6%). We found immune function indicators negatively associated with depressive symptoms (p ＜ .05) and perceived stress and social stigma positively associated with depressive symptoms (p ＜ .01). Stepwise multiple regression analysis indicated that perceived stress and social stigma accounted for 44.4% of depressive symptom variance.Conclusion: Findings suggest that reducing perceived stress and social stigma may positively affect perceived depressive symptoms in this population and may be referenced in future development of related interventions.