An Analysis of Intraspinal Tumors in south Taiwan

南台灣脊髓腫瘤之分析

10.6452/KJMS.199704.0229

鄭子文(Chi-Man Cheang)；黃旭霖(Shiuh-Lin Hwang)；洪純隆(Shen-Long Hwong)

intraspinal tumors ； statistics

The Kaohsiung Journal of Medical Sciences

13卷4期（1997 / 04 / 01）

229 - 236

英文

本研究分析1985.3.1至1995.6.24期間在高雄醫學院腦神經外科接受手術的120例脊髓腫瘤的流行病特性。並與文獻中北台灣及其他國家的結果以盛行率、位置、年齡及性別等項目互相比較。脊髓腫瘤與腦腫瘤的比例約為1：5，比中國大陸、韓國及西方國家較高。 脊髓腫瘤男與女的比例為1.2：1。大部份脊髓腫瘤都是男性較多，但脊膜瘤側以女性為主。脊髓腫瘤發生率依次為神經細胞膜腫瘤、轉移性腫瘤、脊膜瘤、神經膠瘤、先天性腫瘤及血管腫瘤。在東方國家，神經細胞膜腫瘤約佔40%，脊膜瘤約佔10%。在西方國家，兩者都大約佔20%。 先天性腫瘤佔3.3%，在中國大陸卻佔12%，為世界上先天性腫瘤比例最高的國家。神經膠瘤在台灣、中國大陸、泰國、日本及伊朗的比例都約為10%。在西方及印度則為15%。在韓國則為32.3%。 轉移性腫瘤在中國大陸及日植的比例為4.6-5.5%。但在台灣、伊朗及西方國家則為14.2-24.2%。轉移性腫瘤依次是來源不明轉移、肺癌轉移、肝癌轉移、及乳癌轉移。來源不明的轉移性腫瘤比例較高可能是因為追蹤失敗及無屍體解剖的原故。

A series of 120 pathologically verified intraspinal tumors was analyzed for the relative incidence and location of the tumors as well as the distribution of age and sex. These data were compared to series from Taiwan, mainland China, Thailand, Korea, Japan, Iran, India, and countries in the West. The ratio of brain to intraspinal tumors was about 5:1 in Taiwan, higher than those reported in China, Korea, and in the West. The male to female ratio is about six to five. For most tumors, male predominance is noted except for meningioma. The incidence of intraspinal tumors in the order of frequency is nerve sheath cell tumor (NSCT), metastatic tumors, meningioma, glioma, congenital tumors, and vascular tumors. In the East, the incidence of NSCT is about 40%, and meningioma is about 10%. In the West, they are both about 20%. Congenital tumors accounted for only 3.3%. In China, it was about 12% and this is the highest incidence of dysembryoplastic tumors in the world. Glioma has similar incidence (about 10%) in Taiwan, China, Thailand, Japan, and Iran (about 10%), whereas it is about 15% in the West and India. Korea has the highest incidence of glioma. (32.3%). Low incidences of metastatic intraspinal tumors (4.6-5.5%) were noted in China and Japan, but a higher incidence (14.2-24.2%) was seen in Taiwan, Iran, and the West. The most common metastatic tumors in the order of frequency is tumors of unknown origin, lung cancer metastasis, hepatoma, and breast cancer. The high percentage of unknown origin of metastasis may have resulted from loss of follow-up and lack of postmortem studies.