题名

Odour Transduction in Olfactory Receptor Neurons

DOI

10.4077/CJP.2010.AMM038

作者

Jean-Pierre Rospars；Yu-Qiao Gu；Alexandre Grémiaux；Philippe Lucas

关键词

olfactory receptors ； ionic channels ； OBPs ； pheromones ； computer models

期刊名称

The Chinese Journal of Physiology

卷期/出版年月

53卷6期（2010 / 12 / 01）

页次

364 - 372

内容语文

英文
英文摘要

The molecular mechanisms that control the binding of odorant to olfactory receptors and transduce this signal into membrane depolarization are reviewed. They are compared in vertebrates and insects for interspecific (allelochemicals) and intraspecific (pheromones) olfactory signals. Attempts to develop quantitative models of these multistage signalling networks are presented. Computational analysis of olfactory transduction is still in its infancy and appears as a promising area for future developments.
主题分类 醫藥衛生 > 基礎醫學
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