| 题名 |
Trends in Hyperuricemia and Gout Prevalence: Nutrition and Health Survey in Taiwan from 1993-1996 to 2005-2008 |
| 并列篇名 |
高尿酸血症與痛風盛行率的趨勢：臺灣營養健康家戶調查，1993-1996至2005-2008 |
| DOI |
10.6133/apjcn.2011.20.2.20 |
| 作者 |
Shao-Yuan Chuang；Shu-Chen Lee；Yao-Te Hsieh；Wen-Harn Pan |
| 关键词 |
尿酸 ； 飲食型態 ； 趨勢 ； 臺灣營養健康家戶調查 ； 減維度回歸法 ； uric acid ； dietary patterns ； trend ； national survey ； reduced rank regression |
| 期刊名称 |
Asia Pacific Journal of Clinical Nutrition |
| 卷期/出版年月 |
20卷2期（2011 / 06 / 01） |
| 页次 |
301 - 308 |
| 内容语文 |
英文 |
| 中文摘要 |
Hyperuricemia is a recognized risk factor for cardiovascular disease. This study investigated trends in uric acid levels, hyperuricemia and gout among adults in Taiwan from 1993-1996 to 2005-2008, using data collection from, Nutrition and health surveys in Taiwan (NAHSIT) conducted in 1993-1996 and 2005-2008. Information on food frequency, medical history, physical measures and fasting blood parameters were analyzed. Mean uric acid levels decreased between 1993-1996 and 2005-2008 in both genders (6.77 vs 6.59 mg/dL in men and 5.33 vs 4.97 mg/dL in women) and the prevalence of hyperuricemia declined from 25.3% to 22.0% in men (p＜0.0001) and from 16.7% to 9.7% in women (p＜0.0001). However, the prevalence of gout (self-reported) increased (4.74% vs 8.21% in men and 2.19% vs 2.33% in women, p＜0.0001). Reduced rank regression was used to identify dietary patterns that explained significant amounts of variance in uric acid. Frequency of consumption of lean meat, soy products and soymilk, milk, eggs, vegetables, carrots, mushrooms, fruit and coffee were negatively associated with hyperuricemia, whereas consumption of organ meats, bamboo shoots, and soft drinks were positively associated with hyperuricemia. The dietary factor score (DFS) composed of the frequency of above food items decreased from -5.40 to -6.00 between the two surveys (p＜0.0001). In conclusion, uric acid levels and prevalence of hyperuricemia both declined, whilst self-reported gout increased between 1993-1996 and 2005- 2008. Changes in dietary patterns may in part explain the decrease in uric acid levels between the two national surveys. |
| 英文摘要 |
Hyperuricemia is a recognized risk factor for cardiovascular disease. This study investigated trends in uric acid levels, hyperuricemia and gout among adults in Taiwan from 1993-1996 to 2005-2008, using data collection from, Nutrition and health surveys in Taiwan (NAHSIT) conducted in 1993-1996 and 2005-2008. Information on food frequency, medical history, physical measures and fasting blood parameters were analyzed. Mean uric acid levels decreased between 1993-1996 and 2005-2008 in both genders (6.77 vs 6.59 mg/dL in men and 5.33 vs 4.97 mg/dL in women) and the prevalence of hyperuricemia declined from 25.3% to 22.0% in men (p＜0.0001) and from 16.7% to 9.7% in women (p＜0.0001). However, the prevalence of gout (self-reported) increased (4.74% vs 8.21% in men and 2.19% vs 2.33% in women, p＜0.0001). Reduced rank regression was used to identify dietary patterns that explained significant amounts of variance in uric acid. Frequency of consumption of lean meat, soy products and soymilk, milk, eggs, vegetables, carrots, mushrooms, fruit and coffee were negatively associated with hyperuricemia, whereas consumption of organ meats, bamboo shoots, and soft drinks were positively associated with hyperuricemia. The dietary factor score (DFS) composed of the frequency of above food items decreased from -5.40 to -6.00 between the two surveys (p＜0.0001). In conclusion, uric acid levels and prevalence of hyperuricemia both declined, whilst self-reported gout increased between 1993-1996 and 2005- 2008. Changes in dietary patterns may in part explain the decrease in uric acid levels between the two national surveys. |
| 主题分类 |
醫藥衛生 >
預防保健與衛生學 |
| 被引用次数 |
