癲癇與懷孕：一病例報告及文獻回顧

Epilepsy and Pregnancy: A Case Report and Review of Literature

簡陳榮(Chen-Lung Chien)；師明哲(Ming-Che Shih)

癲癇連續狀態 ； 癲癇性懷孕 ； EpiIeptic pregnancy ； Status epilepticus

Journal of Medical Sciences

6卷2期（1985 / 11 / 01）

211 - 214

繁體中文

本院最近有一癲癇性懷孕（epileptic pregnancy）的病人，因懷孕時沒有連續服用dilantin及調整其劑量，而於懷孕最後三個月時癲癇發作了兩次；產婦於懷孕足月時接受剖腹產手術，出生一重3,450 gm的男嬰，Apgar計分在一分鐘時是8，五分鐘時是9，沒有先天性畸型發生。產婦手術後病情穩定且恢復迅速。有癲癇病史的病人懷孕時，約有半數在其懷孕過程中癲癇很難加以控制。如何適當地使用抗癲癇藥物來控制癲癇，使不發作，同時不致因使用抗癲癇藥物而造成胎兒畸型，是處理癲癇性懷孕二個最重要的目的。

Recently, there was a case of epileptic pregnancy admitted in our hospital. The 19-year-old patient was treated with antiepileptic drug (dilantin) irregularly. Two fits of seizure were noted during the third trimester. A 3,450 gm male baby was delivered by cesarean section at term. Apgar scores were 8 and 9 at 1 minute and 5 minutes respectively. There was no congenital malformation noted. The patient recovered rapidly after the operation. About half of this type pregnant patients with history of epilepsy will become very difficult to control the seizure during the whole course of pregnancy. The major concerns in these pregnant epileptic patients are loss of seizure control and the teratogenic effect of antiepileptic drugs on the fetus. Recommendations for management of epilepsy in pregnancy were also made in this report.