Hepatoblastoma in a Male Adult: Report of a Case

發生於成年男性的肝母細胞癌：一病例報告

10.6557/GJT.201312_30(4).0004

陳彥樺(Yan-Hua Chen)；許秉毅(Ping-I Hsu)；陳海雄(Hoi-Hung Chan)；蔡維倫(Wei-Lun Tsai)；陳文誌(Wen-Chi Chen)；王惠民(Huay-Min Wang)；黎國洪(Kwok-Hung Lai)；陳玉佳(Yu-Chia Chen)；黃哲勳(Jer-Shyung Huang)；謝品本(Pin-Pen Hsieh)；游偉雯(Wei-Wen Yu)

肝母細胞癌 ； 成年人 ； hepatoblastoma ； adult

臺灣消化醫學雜誌

30卷4期（2013 / 12 / 01）

314 - 319

英文

肝母細胞癌是一種少見的肝臟惡性腫瘤，且通常發生於三歲以下的幼童。此腫瘤甚少發生於成年人，是一種極少見的成人原發性肝臟惡性腫瘤。一位84歲的男性因逐漸的食慾不振及體重減輕已五個月的時間而來求診。磁振造影檢查發現肝臟有一在動脈相會顯影而在延遲相則被淡化的腫瘤。初步放射線科的報告為肝細胞癌。血清胎兒球蛋白的值為8849 ng/ml。於是病患接受了肝臟第五個segment的切除手術。令人意外地，病理切片證實此肝腫瘤為一包含了表皮及間質成分的混和型肝母細胞癌，且合併有部分的畸胎型態。總結而言肝母細胞癌應列入成人肝臟惡性腫瘤的鑑別診斷之一。

Hepatoblastoma is a rare malignant tumor of the liver, usually occurring in the first three years of life. Hepatoblastomas in adults are unusual and are an exceptional cause of primary malignant liver tumor in adult patients. An 84-year-old man suffered from progressively poor appetite and weight loss for 5 months. Magnetic resonance examination revealed a tumor was enhanced in the arterial phase and washed out in the late phase on dynamic studies. Hepatocellular carcinoma was diagnosed by the radiologists. Serum α-fetoprotein level was 8849 ng/ml. Subsequently, a S5 segmentectomy was performed. To our surprise, pathologic examination of the resected liver tumor confirmed the diagnosis of hepatoblastoma of a mixed epithelial and mesenchymal type with teratoid features. We concluded that hepatoblastoma should be included in the differential diagnostic list of malignant liver tumor in adults.