Intracranial Hemangiopericytoma with Multiple Extracranial Metastasis - Case Report and Literature Review

顱內血管外皮細胞瘤併發多處顱外轉移－病例報告及文獻回顧

10.6440/TZUCMJ.199712.0307

陳金城(Jin-Cherng Chen)；李和明(Her-Ming Lee)；陳怡龍(Yi-Long Chen)；林主一(Chu-Yi Lin)；高明見(Ming-Chien Kao)

血管外皮細胞瘤 ； 腦膜瘤 ； 轉移 ； hemangiopericytoma ； meningioma ； metastasis

慈濟醫學雜誌

9卷4期（1997 / 12 / 01）

307 - 313

英文

本文報告一例顱內血管外皮細胞瘤。有多發性顱外轉移，包括肝臟、肺臟及頸椎等。病人是一個四十一歲女性。在西元1986年因左側矢竇旁腫瘤而接受開顱術並腫瘤切除。此後，因腫瘤復發而於1990及1992年分別接受腫瘤切除手術。病人於1994年又因後顱窩腫瘤接受枕骨下顱骨切除術並腫瘤切除，住院期間發現左上肺葉腫瘤及左肝左側葉腫瘤乃接受胸腔肺葉腫瘤契型切除，及腹腔鏡肝葉腫瘤部分切除。1995年五月及十一月分別接受右側小腦橋腦角腫瘤及頸椎腫瘤切除。所有以上八次手術之病理組織檢查顯示皆為血管外皮細胞瘤。本文討論此病之臨床、放射、病理特性及與腦膜瘤之不同點。(慈濟醫學 19947;9:307-313)

Hemangiopericytoma is a rare type of vascular tumor that is highly aggressive and has a high recurrence rate. We report the case of a 44 year old woman in whom intracranial meningeal hemangiopericytoma with multiple extracranial metastasis involving the liver, left lung, cervical and lumbosacral spine was diagnosed. She had previously received surgery to excise the left parasagittal tumor in 1986 and had undergone two subsequent operations for tumor recurrence in 1990 and 1992, respectively. She had also received an operation to excise a midline posterior fossa tumor in 1994. A lung tumor in the left upper lobe and a liver mass in the lateral segment of the left hepatic lobe were also discovered during her hospitalization in 1994, and video-assissted thoracoscopic wedge resection of the left lung tumor and laparoscopic biopsy of the liver mass were performed. In 1995, resection of a right side cerebellpontine angle tumor and a subsequent operation for resection of a cervical spinal tumor were performed. The histopathology of tissue specimens obtained in all of the above mentioned eight operations revealed meningeal hemangiopericytoma. The clinical, radiological and pathological features of the meningeal hemangiopericytoma of the patient are presented with a discussion of difference in the histopathological features of meningioma and meningeal hemangiopericytoma.(Tzu Chi Med J 1997;9:307-313)