Japanese Encephalitis with Fulminant Neurogenic Pulmonary Edema-A Case Report

日本腦炎合併猛爆型神經性肺水腫－病例報告

10.6440/TZUCMJ.199912.0365

許永祥(Yung-Hsiang Hsu)；羅富進(Fuh-Jinn Luo)；謝文儒(Wen-Ju Shieh)

日本腦炎 ； 免疫組織化學染色 ； 猛爆型神經性肺水腫 ； Japanese encephalitis ； immunohistochemistry stain ； fulminant neurogenic pulmonary edema

慈濟醫學雜誌

11卷4期（1999 / 12 / 01）

365 - 369

英文

日本腦炎在台舉夏李有零星偶發個案報告，這三年來台灣確診日本腦炎病例分別是85年12例、86年6例、87年22例。我們以病理解剖證實一例日本腦炎病患死邶神經性肺水腫。這是一位35歲男性患因高燒和畏冷超過三天，於87年6月19日23:28到門諾醫院急診求診，回家後，突然於6月22日早上6:30死亡，法醫病理解剖以日本腦炎單株抗體做免疫組織化學染色證實為日本腦炎。出血性肺水腫是其致命死因。本文將探討神經性肺水腫的機轉。(慈濟醫學 1999; 11:365-369)

Japanese encephalitis has a seasonal clustering in summer in Taiwan. Only sporadic cases are reported each year. We present one case with Japanese encephalitis who died of fulminant neurogenic pulmonary edema. A 35-year-old man suffered from fever and chills for 3 days. He visited Mennonite Christian Hospital at 23:28 on June 19, 1998. Sudden death occurred at 6:30 on June 22. Forensic autopsy proved Japanese encephalitis by immunohistochemistry staining using mouse anti-JE antibody. Hemorrhagic pulmonary edema was the cause of death. The mechanism of neurogenic pulmonary edema is discussed.(Tzu Chi Med J 1999; 11:365-369)