文獻回顧－肌少症與衰弱症

Review: Sarcopenia and Frailty

10.6314/JIMT.2014.25(3).01

吳雅汝(Ya-Ju Wu)；周怡君(Yi-Chun Chou)；詹鼎正(Ding-Cheng Chan)

老年人（The elderly） ； 肌少症（Sarcopenia） ； 衰弱症（Frailty）

內科學誌

25卷3期（2014 / 06 / 01）

131 - 136

繁體中文

隨著人口老化，肌少症及衰弱症此兩個老年病症候群逐漸受到重視。雖然兩者定義尚未明確，但目前已知肌少症的核心概念為肌肉的力量、質量，或是生理表現的下降；衰弱症則表示個體多項生理系統儲備能力下降，超乎其原來年紀該有的程度，其核心表現包括體重減輕、肌力下降，以及活動力變弱等。肌少和衰弱症有相似的成因，也都會造成臨床的不利結果，目前營養及運動的介入被視為可以預防和改善衰弱及肌少症的有效介入方法。本文將簡介肌少症及衰弱症、兩者之關聯，並提供適當的介入策略，以提供內科醫師對此兩個老年病症候群的認識。

As the population aging, the two geriatric syndromes, sarcopenia and frailty, become more prominent. However, the definitions of these two geriatric syndromes are not unified. The core concept of sarcopenia is reduced muscle strength, muscle mass and/or decreased physical performance. Frailty is multi-system impairment associated with decreased physiological reservation and could not maintain one's daily activity compared to individuals of same age. The core presentations include body weight loss, decrease muscle strain and activity. Sarcopenia and frailty have several common causes, and possibly result in clinical adverse outcomes. Currently, adequate nutrition and exercise are effective intervention to prevent and treat these two syndromes. This review will introduce the definition of sarcopenia and frailty, association between them, and appropriate intervention. It also provides internal medicine doctors an understanding of these two syndromes.