| 题名 |
食道鱗狀上皮癌現今治療進展 |
| 并列篇名 |
Basic and Clinical Reviews of Esophageal Squamous Cell Carcinoma |
| DOI |
10.6314/JIMT.201802_29(1).04 |
| 作者 |
林柏任(Bou-Zenn Lin)；吳文傑(Wen-Chieh Wu)；周益聖(Yi-Sheng Chou)；徐博奎(Po-Kuei Hsu)；林志陵(Chih-Lin Lin)；廖麗瑛(Li-Ying Liao)；陳冠仰(Kuan-Yang Chen) |
| 关键词 |
食道癌(Esophageal cancer) ； 鱗狀上皮癌(Squamous cell carcinoma) ； 內視鏡黏膜下切除(Endoscopic submucosal resection) ； 微創食道切除術(Minimally invasive esophagectomy) |
| 期刊名称 |
內科學誌 |
| 卷期/出版年月 |
29卷1期（2018 / 02 / 01） |
| 页次 |
28 - 37 |
| 内容语文 |
繁體中文 |
| 中文摘要 |
食道癌位居國人2016年十大癌症死因第九位，且男性死亡率遠遠高於女性，彼此相差十五倍有餘。而食道鱗狀上皮癌占了所有食道癌的八成，是一種高度侵襲性的癌症，只有不到四分之一的病人能活超過五年；更因為嚴重的腫瘤相關併發症如無法進食、廔管等，令人聞之色變。不過近年來隨著內視鏡技術的進步、化療和放射治療的發展，能夠更早的發現及更好的治療食道癌，大大改善了病人的預後。本文回顧了最近幾年食道鱗狀上皮癌的最新發展和臨床研究報告，從盛行率、致病因子、基因、診斷和治療方法等方面來剖析食道鱗狀上皮癌，期待對於臨床工作者有所幫助。 |
| 英文摘要 |
In 2016, esophageal cancer was the ninth most common cause of cancer death in Taiwan. Moreover, the mortality rate in men was 15 times higher than that in women. Squamous cell carcinoma accounts for 80% of esophageal cancer. It is a highly invasive cancer, and symptoms include dysphagia, fistulas, and bleeding. Less than 25% of patients survive for 5 years or more. Recent progress in endoscopic techniques has led to earlier detection of esophageal cancer, and with developments in chemoradiotherapy the prognosis has improved greatly. The present article reviews the latest developments and clinical research in esophageal squamous cell carcinoma, including the prevalence, pathogenic mechanisms, and genetic factors. Diagnostic modalities and current treatment options are discussed to help clinicians. |
| 主题分类 |
醫藥衛生 >
內科 |
| 被引用次数 |
