早產兒視網膜病變之冷凍治療

Cryotherapy for Retinopathy of Prematurity

10.30048/ACTASOS.198805.0171

劉榮宏(Jorn-Hon Liu)；黃書紳(Shu-Sheng Huang)

Retinopathy of Prematurity ； Extraretinal fobrovascular proliferation ； cryotherapy

台灣眼科醫學會會刊

27卷2期（1988 / 05 / 01）

977 - 980

繁體中文

本篇報告使用冷凍法治療活躍性早產兒視網膜病變之結果。總共治療8位病人15隻眼睛，包括14隻有第三期病變加上plus disease及一隻併有初期局部視網膜剝離之第四期病變者。病患生下時妊娠週數平均28.5週，治療時年齡平均為10.8週，11隻眼睛只接受一次治療，另4隻接受兩次之治療。結果有13隻眼睛新生血管完全消失、未留下任何後遺病灶，有1隻眼睛形成視神經乳頭拉曳，另一隻演變成第五期視網膜全剝離之病變。經過六到十二個月之觀察未發現有任何治療上之合併症。從本觀察之結果顯示冷凍療法對活躍性新生血管增生有快速抑制作用，對第三期早產兒視網膜病變有治療效益。

We present a series of active retinopathy of prematurity treated by cryopexy. A total of 15 eyes from 8 patients were treated between January and June 1987. At the time of surgery, 14 eyes were in the stage Ⅲ ROP with plus disease, and another eye just progressed from stage Ⅲ to stage Ⅳ with small localized detachment. The average gestational age. at birth was 28.5 weeks. The average age at the time of surgery was 10.8 weeks. Eleven eyes underwent one session of treatment while other 4 eyes two. The results showed 13 eyes had complete resolution without sequela, 1 eye had a dragging disc and another eye developed total retinal detachment. After a follow-up of 6 to 12 months, there was no therapeutical complication found in these eyes. Our results demonstrate that cryopexy is very effective for the active neovascularization and is useful for stage Ⅲ retinopathy of prematurity.