Laboratory Investigation of a Suspected Enterovirus 71 Outbreak in Central Taiwan

10.6525/TEB.199912_15(12).0001

S. Y. Wang；C. L. Lin；H. C. Sun；H. Y. Chen

Epidemiology Bulletin

15卷12期（1999 / 12 / 01）

215 - 219

英文

Enterovirus 71 (EV71) was first identified in the US in 1969. It was also, of all known enteroviruses, the last one identified. Subsequently, infections have been reported from all over the world. The virus can induce, in addition to some special clinical symptoms such as hand-food-and-mouth disease (HFMD) and herpangina, serious complications of the nervous system such as meningitis and encephalitis. Its pathogenicity therefore is high. Between January and May 1999, of all suspected EV71 case reported by contract laboratories in the northern, central, southern, and eastern parts of Taiwan, only three were confirmed. However, since June 1999, one provisional medical center in central Taiwan unusually reported in series six EV71 cases. To avoid any panic of the public resulting from inadequate evaluation, Division of Viral Diseases and Division of Surveillance of Center for Disease Control in Taiwan immediately conducted relevant laboratory and epidemiological investigations of the incident. By visiting cases, understanding the laboratory procedures of the said provisional medical center, and further laboratory testing of specimens, it was decided that the six cases were Coxsackie A16 virus infections.

1. 李政頡(2017)。咔唑與苯並咪唑碳氮連接之雙極性衍生物為主體材料之藍色磷光及熱活性型螢光有機發光二極體之研究。臺灣大學光電工程學研究所學位論文。2017。1-57。