Falsely Upstaged Breast Cancer by 18F-2-Fluoro-2-Deoxy-D-Glucose Positron Emission Tomography in a Patient with Concomitant Pulmonary Tuberculosis

氟－18-去氧葡萄糖正子斷層攝影在一位乳癌病患合併有肺結核所造成乳癌腫瘤分級假性上昇之病例報告

10.6332/ANMS.2001.005

張秀萍(Hsiu-Ping Chang)；閻紫宸(Tzu-Chen Yen)；陳訓徹(Shin-Cheh Chen)

正子斷層攝影 ； 氟－18-去氧葡萄糖 ； 乳癌 ； 肺結核 ； positron emission tomography ； FDG ； breast carcinoma ； tuberculosis

核子醫學雜誌

20卷1期（2007 / 03 / 01）

33 - 38

英文

長期使用類固醇而使免疫力受抑制之病患中，遭受伺機性感染（例如化膿性細菌、李斯特菌屬、黴菌、退伍軍人菌屬、皰疹病毒和結核桿菌等）並非少見。在癌症病患伴隨伺機性感染時，氟－18-去氧葡萄糖正子斷層攝影可能無法正確分辨良性或惡性病灶。我們報告一位肺部有氟－18-去氧葡萄糖正子聚積而疑似肺部轉移所造成乳癌腫瘤分期假性上昇的病例。術前的電腦斷層導引組織切片檢查證實此病患是乳癌伴隨肺結核感染。

Immunocompromised patients undergoing long-term steroid therapy may be afflicted with opportunistic infections such as pyogenic bacteria, Listeria, fungi, legionellosis, herpes viruses, and tuberculosis. For cancer patients with concomitant opportunistic infections, 18F-2-fluoro-2-deoxyglucose (FDG) positron emission tomography (PET) may not able to clearly distinguish benign lesions from malignant. Herein, we report a case that was falsely upstaged as lung metastases by FDG PET. A pre-operative CT-guided biopsy was performed, which identified the patient as suffering from breast cancer with concomitant pulmonary tuberculosis.