Small Cell Carcinoma of External Auditory Canal: A Case Report

外耳道小細胞癌：病例報告

10.6316/TRO/201017(2)145

沈佳韋(Chia-Wei Shen)；胡渝昌(Yu-Chang Hu)；賴韋銘(Wei-Ming Lai)；陳建勳(Chien-Hsun Chen)；梁頌文(Chung-Man Leung)；張國楨(Kuo-Chen Chang)；張慶雄(Ching-Hsiung Chang)

小細胞癌 ； 肺外 ； 外耳道 ； 放射治療 ； Small cell carcinoma ； Extrapulmonary ； External auditory canal ； Radiotherapy

放射治療與腫瘤學

17卷2期（2010 / 06 / 01）

145 - 151

英文

肺外小細胞癌很少在頭頸部發現，我們報告一個51歲女性的右外耳道小細胞癌。廣泛性切除腫瘤後，又發現右頸部淋巴結。她接受了6個療程的化學治療，使用的藥物是cisplatin和etoposide。斷層掃描顯示淋巴結腫大已消失，且原發部位沒有腫瘤復發。之後她再接受局部強度調控放射治療，腫瘤床的劑量是60Gy/30次，局部淋巴結的劑量是54Gy/30次，放射治療很順利完成。然而，病人在放療過程中發生了肝轉移，最後距離初診斷12個月後死亡。我們相信，對於肺外小細胞癌來說，雖然放射治療對局部控制有幫助，但是化學治療還是最重要的。

Extrapulmonary small cell carcinoma arising from head and neck is extremely rare. We report a 51-year-old woman with small cell carcinoma of right external auditory canal. A wide excision surgery was performed. Right side neck lymph node metastasis was found after operation. She underwent chemotherapy with 6 courses of cisplatin and etoposide. The posttreatment CT scan of head and neck disclosed complete remission of lymphadenopathy and no local recurrence of primary tumor. Then she received local radiotherapy using IMRT technique with 60 Gy in 30 fractions to tumor bed and 54 Gy in 30 fractions to regional lymphatics. The treatment course of radiation was completed smoothly. However, the patient developed liver metastases during the radiotherapy course and then died 12 months after the initial diagnosis. We believe that although radiotherapy have benefit for local control, chemotherapy is of the most importance for extrapulmonary small cell carcinoma.