運動與碳水化合物對於餐後血脂的影響

The Influence of Exercise and Carbohydrate on Postprandial Lipemia

10.6223/qcpe.2603.201209.1502

楊璁人(Tsung-Jen Yang)；邱志暉(Chih-Hui Chiu)；巫錦霖(Ching-Lin Wu)

三酸甘油脂 ； 心血管疾病 ； 高密度脂蛋白膽固醇 ； triglyeride ； CVD ； HDL-C

中華體育季刊

26卷3期（2012 / 09 / 01）

291 - 297

繁體中文

高濃度的血漿三酸甘油脂（triglyceride, TG）是心血管疾病（cardiovascular disease, CVD）的主要風險因子之一。用餐後6小時，血漿TG的濃度依然比禁食狀態下的濃度高，而人體自吃完早餐之後，長時間都處於餐後高濃度血脂肪的狀態，因此如何有效提高餐後血脂肪的清除率，對於降低CVD的風險是相當重要的。研究指出，餐前單一次的運動就能有效降低餐後的血漿TG濃度，並提升血液中的高密度脂蛋白膽固醇（high-density lipoprotein cholesterol, HDL-C）的濃度。運動對於餐後血漿TG濃度的影響和運動中所消耗的能量、運動強度、運動種類及運動的持續時間皆有關。在餐前12－16小時運動，比餐前1小時或是餐後的運動，對於降低血脂肪的影響更為顯著。此外，攝取過多的碳水化合物也會造成餐後血漿TG濃度的增加。運動能夠降低因攝取高碳水化合物後的血漿TG的濃度，然而，當運動結束後使用碳水化合物將運動所消耗能量回補時，運動改善餐後高血脂的效果也將會被抑制。

The high concentration of plasma triglyceride (TG) is one of the major risk factors of cardiovascular disease (CVD). Postprandial lipemia phenomena may last for over 6 hours after a meal. People spend most time of the day in postprandial state after breakfast. Therefore, to reduce postprandial TG concentration is an important task for lowering CVD risk. It has been reported that the single bout of exercise could decrease the postprandial TG concentration and increase the high density lipoprotein-cholesterol (HDL-C) concentration. The scale of exercise reducing postprandial plasma TG concentrations was influenced by the energy expenditure, exercise intensity, exercise duration, and type of exercise. Exercise at 12-14 hours before the meal reduced the postprandial lipemia greater than exercise at 1 hour before the meal. In addition, ingestion of carbohydrate might increase postprandial lipemia. Exercise has been effective for lowering postprandial lipemia after high carbohydrate diet. However, when the energy expenditure from exercise was refilled by carbohydrate, the exercise effect on reducing postprandial lipemia might be diminished.

1. Aldred, H. E.,Perry, I. C.,Hardman, A. E.(1994).The effect of a single bout of brisk walking on postprandial lipemia in normolipidemic young adults.Metabolism: Clinical and Experimental,43(7),836-841.
2. Alvarez, J. A.,Higgins, P. B.,Oster, R. A.,Fernandez, J. R.,Darnell, B. E.,Gower, B. A.(2009).Fasting and postprandial markers of inflammation in lean and overweight children.The American Journal of Clinical Nutrition,89(4),1138-1144.
3. Burns, S. F.,Broom, D. R.,Miyashita, M.,Ueda, C.,Stensel, D. J.(2006).Increased postprandial triacylglycerol concentrations following resistance exercise.Medicine & Science in Sports & Exercise,38(3),527-533.
4. Dasu, M. R.,Jialal, I.(2011).Free fatty acids in the presence of high glucose amplify monocyte inflammation via toll-like receptors.American Journal of Physiology, Endocrinology and Metabolism,300(1),E145-154.
5. Eckel, R. H.(1989).Lipoprotein lipase. A multifunctional enzyme relevant to common metabolic diseases.The New England Journal of Medicine,320(16),1060-1068.
6. Fernandez-Real, J. M.,Ricart, W.(2003).Insulin resistance and chronic cardiovascular inflammatory syndrome.Endocrine Reviews,24(3),278-301.
7. Freese, E. C.,Levine, A. S.,Chapman, D. P.,Hausman, D. B.,Cureton, K. J.(2011).Effects of acute sprint interval cycling and energy replacement on postprandial lipemia.Journal of Applied Physiology,111(6),1584-1589.
8. Gill, J. M.,Hardman, A. E.(2003).Exercise and postprandial lipid metabolism: An update on potential mechanisms and interactions with high-carbohydrate diets (review).The Journal of Nutritional Biochemistry,14(3),122-132.
9. Gill, J. M.,Herd, S. L.,Hardman, A. E.(2002).Moderate exercise and post-prandial metabolism: Issues of dose-response.Journal of Sports Sciences,20(12),961-967.
10. Gill, J. M.,Herd, S. L.,Vora, V.,Hardman, A. E.(2003).Effects of a brisk walk on lipoprotein lipase activity and plasma triglyceride concentrations in the fasted and postprandial states.European Journal of Applied Physiology,89(2),184-190.
11. Harrison, M.,Murphy, R. P.,O''Connor, P. L.,O''Gorman, D. J.,McCaffrey, N.,Cummins, P. M.,Moyna, N. M.(2009).The endothelial microparticle response to a high fat meal is not attenuated by prior exercise.European Journal of Applied Physiology,106(4),555-562.
12. Harrison, M.,O''Gorman, D. J.,McCaffrey, N.,Hamilton, M. T.,Zderic, T. W.,Carson, B. P.,Moyna, N. M.(2009).Influence of acute exercise with and without carbohydrate replacement on postprandial lipid metabolism.Journal of Applied Physiology,106(3),943-949.
13. Herd, S. L.,Hardman, A. E.,Boobis, L. H.,Cairns, C. J.(1998).The effect of 13 weeks of running training followed by 9 d of detraining on postprandial lipaemia.The British Journal of Nutrition,80(1),57-66.
14. Jeppesen, J.,Hein, H. O.,Suadicani, P.,Gyntelberg, F.(1997).Relation of high TG-low HDL cholesterol and LDL cholesterol to the incidence of ischemic heart disease. An 8-year follow-up in the copenhagen male study.Arteriosclerosis, Thrombosis, and Vascular Biology,17(6),1114-1120.
15. Katsanos, C. S.,Grandjean, P. W.,Moffatt, R. J.(2004).Effects of low and moderate exercise intensity on postprandial lipemia and postheparin plasma lipoprotein lipase activity in physically active men.Journal of Applied Physiology,96(1),181-188.
16. Kiens, B.,Lithell, H.(1989).Lipoprotein metabolism influenced by training-induced changes in human skeletal muscle.The Journal of Clinical Investigation,83(2),558-564.
17. Koutsari, C.,Hardman, A. E.(2001).Exercise prevents the augmentation of postprandial lipaemia attributable to a low-fat high-carbohydrate diet.The British Journal of Nutrition,86(2),197-205.
18. Mankowitz, K.,Seip, R.,Semenkovich, C. F.,Daugherty, A.,Schonfeld, G.(1992).Short-term interruption of training affects both fasting and post-prandial lipoproteins.Atherosclerosis,95(2-3),181-189.
19. Mitchell, J. B.,Rowe, J. R.,Shah, M.,Barbee, J. J.,Watkins, A. M.,Stephens, C.,Simmons, S.(2008).Effect of prior exercise on postprandial triglycerides in overweight young women after ingesting a high-carbohydrate meal.International Journal of Sport Nutrition and Exercise Metabolism,18(1),49-65.
20. Miyashita, M.,Burns, S. F.,Stensel, D. J.(2008).Accumulating short bouts of brisk walking reduces postprandial plasma triacylglycerol concentrations and resting blood pressure in healthy young men.The American Journal of Clinical Nutrition,88(5),1225-1231.
21. Miyashita, M.,Burns, S. F.,Stensel, D. J.(2006).Exercise and postprandial lipemia: Effect of continuous compared with intermittent activity patterns.The American Journal of Clinical Nutrition,83(1),24-29.
22. Nordestgaard, B. G.,Benn, M.,Schnohr, P.,Tybjaerg-Hansen, A.(2007).Nonfasting triglycerides and risk of myocardial infarction, ischemic heart disease, and death in men and women.JAMA,298(3),299-308.
23. Pafili, Z. K.,Bogdanis, G. C.,Tsetsonis, N. V.,Maridaki, M.(2009).Postprandial lipemia 16 and 40 hours after low-volume eccentric resistance exercise.Medicine & Science in Sports & Exercise,41(2),375-382.
24. Petitt, D. S.,Cureton, K. J.(2003).Effects of prior exercise on postprandial lipemia: A quantitative review.Metabolism: Clinical and Experimental,52(4),418-424.
25. Podl, T. R.,Zmuda, J. M.,Yurgalevitch, S. M.,Fahrenbach, M. C.,Bausserman, L. L.,Terry, R. B.,Thompson, P. D.(1994).Lipoprotein lipase activity and plasma triglyceride clearance are elevated in endurance-trained women.Metabolism: Clinical and Experimental,43(7),808-813.
26. Seip, R. L.,Angelopoulos, T. J.,Semenkovich, C. F.(1995).Exercise induces human lipoprotein lipase gene expression in skeletal muscle but not adipose tissue.The American Journal of Physiology,268(2 Pt 1),E229-236.
27. Seip, R. L.,Mair, K.,Cole, T. G.,Semenkovich, C. F.(1997).Induction of human skeletal muscle lipoprotein lipase gene expression by short-term exercise is transient.The American Journal of Physiology,272(2 Pt 1),E255-261.
28. Shin, Y.,Park, S.,Choue, R.(2009).Comparison of time course changes in blood glucose, insulin and lipids between high carbohydrate and high fat meals in healthy young women.Nutrition Research and Practice,3(2),128-133.
29. Siri-Tarino, P. W.,Sun, Q.,Hu, F. B.,Krauss, R. M.(2010).Saturated fat, carbohydrate, and cardiovascular disease.The American Journal of Clinical Nutrition,91(3),502-509.
30. Thompson, P. D.,Crouse, S. F.,Goodpaster, B.,Kelley, D.,Moyna, N.,Pescatello, L.(2001).The acute versus the chronic response to exercise.Medicine & Science in Sports & Exercise,33(6 Suppl),S438-445.
31. Tsetsonis, N. V.,Hardman, A. E.,Mastana, S. S.(1997).Acute effects of exercise on postprandial lipemia: A comparative study in trained and untrained middle-aged women.The American Journal of Clinical Nutrition,65(2),525-533.
32. Wu, C. L.,Nicholas, C.,Williams, C.,Took, A.,Hardy, L.(2003).The influence of high-carbohydrate meals with different glycaemic indices on substrate utilisation during subsequent exercise.The British Journal of Nutrition,90(6),1049-1056.
33. Zhang, J. Q.,Ji, L. L.,Fogt, D. L.,Fretwell, V. S.(2007).Effect of exercise duration on postprandial hypertriglyceridemia in men with metabolic syndrome.Journal of Applied Physiology,103(4),1339-1345.
34. Zhang, J. Q.,Thomas, T. R.,Ball, S. D.(1998).Effect of exercise timing on postprandial lipemia and HDL cholesterol subfractions.Journal of Applied Physiology,85(4),1516-1522.
35. Zotou, E.,Magkos, F.,Koutsari, C.,Fragopoulou, E.,Nomikos, T.,Sidossis, L. S.,Antonopoulou, S.(2010).Acute resistance exercise attenuates fasting and postprandial triglyceridemia in women by reducing triglyceride concentrations in triglyceride-rich lipoproteins.European Journal of Applied Physiology,110(4),869-874.

1. 楊美玲、楊佳元、吳柏翰(2018)。高強度爆發力訓練對於餐後血脂肪之影響。運動表現期刊，5(1)，1-12。