题名

樹脂製造及應用產業勞工多溴二苯醚暴露評估研究

并列篇名

Exposure Assessment of Polybrominated Diphenyl Ethers (PBDEs) for Workers in Synthetic Resin Industry

DOI

10.7005/JOSH.201012.0442

作者

劉家瑋(Chia-Wei Liu)；陳重羽(Chung-Yu Chen)；吳幸娟(Hsing-Chuan Wu)；李聯雄(Lien-Hsiung Li)；石東生(Tung-Sheng Shih)；李俊璋(Ching-Chang Lee)

关键词

樹脂製造業 ； 作業勞工 ； 血液 ； 多溴二苯醚 ； 甲狀腺荷爾蒙 ； Flame retardative resin industry ； Worker ； serum ； PBDE ； Thyroid hormones

期刊名称

勞工安全衛生研究季刊

卷期/出版年月

18卷4期（2010 / 12 / 01）

页次

442 - 457

内容语文

繁體中文
中文摘要

In Taiwan, the highest amount of Deca-BDE was used in synthetic resin industry since 2003 to 2006 year. The aims of this study are to determine the association between serum levels of 22 PBDE congeners and health index (13 blood biochemistry and 5 hormone examinations) for workers of a representative synthetic resin plant in southern Taiwan, and then to integrate health outcomes, exposure matrix and time activity pattern to assess the occupational PBDEs exposure and health outcomes. 41 workers were grouped to three groups including manufacture (high exposure), processing (medium exposure), and officers (low exposure) by job title, PBDEs exposure possibility and time-activities data were also investigated for double-check. The average serum PBDEs levels were 1149.11, 491.59 and 102.42 ng/g lipid in high, medium and low exposure groups, respectively. The average level of PBDEs in high exposure group was significantly higher than those in other groups (p＜0.0001). The dominant congeners in serum samples were BDE-209, BDE-197 and BDE-207. Moreover, the T3/T4 was significantly correlated with increasing levels of total PBDEs (p=0.0117), BDE-206(p=0.0345), BDE-207 (p=0.0034) and BDE-197 (p=0.003). We further divided all workers into two groups by serum PBDE levels, and we found the T4 levels in high serum PBDE group were significantly lower than low serum PBDE group (p=0.0220). It implied that T4 levels may be decreased by elevated PBDEs levels. In conclusion, we recommend that the manufacturing process need to improve and the workers in synthetic resin industry should enhance hazard education and equip personal protective equipments. We also suggested that PBDEs occupational exposure workers should check on T4 level regularly.
英文摘要

In Taiwan, the highest amount of Deca-BDE was used in synthetic resin industry since 2003 to 2006 year. The aims of this study are to determine the association between serum levels of 22 PBDE congeners and health index (13 blood biochemistry and 5 hormone examinations) for workers of a representative synthetic resin plant in southern Taiwan, and then to integrate health outcomes, exposure matrix and time activity pattern to assess the occupational PBDEs exposure and health outcomes. 41 workers were grouped to three groups including manufacture (high exposure), processing (medium exposure), and officers (low exposure) by job title, PBDEs exposure possibility and time-activities data were also investigated for double-check. The average serum PBDEs levels were 1149.11, 491.59 and 102.42 ng/g lipid in high, medium and low exposure groups, respectively. The average level of PBDEs in high exposure group was significantly higher than those in other groups (p＜0.0001). The dominant congeners in serum samples were BDE-209, BDE-197 and BDE-207. Moreover, the T3/T4 was significantly correlated with increasing levels of total PBDEs (p=0.0117), BDE-206(p=0.0345), BDE-207 (p=0.0034) and BDE-197 (p=0.003). We further divided all workers into two groups by serum PBDE levels, and we found the T4 levels in high serum PBDE group were significantly lower than low serum PBDE group (p=0.0220). It implied that T4 levels may be decreased by elevated PBDEs levels. In conclusion, we recommend that the manufacturing process need to improve and the workers in synthetic resin industry should enhance hazard education and equip personal protective equipments. We also suggested that PBDEs occupational exposure workers should check on T4 level regularly.
主题分类 醫藥衛生 > 預防保健與衛生學
醫藥衛生 > 社會醫學
社會科學 > 社會學
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