老年第一型雙相情感障礙症病患的認知功能障礙

10.29478/TJP.200406.0005

蘇宗偉；李信謙；陳喬琪；蔡尚穎

雙相情感障礙症 ； 老化 ； 認知障礙 ； 社會心理功能

台灣精神醫學

18卷2期（2004 / 06 / 01）

119 - 126

繁體中文

目的：本研究旨在了解老年第一型雙相情感障礙症（Bipolar I disorder）患者的人口學基本特徵，評估其認知功能狀態，且探討認知功能障礙者的特徵。方法：收集符合DSM-IV第一型雙相情感障礙症（Bipolar I disorder）年齡已達60歲以上的患者，以病歷回溯、家屬確認、並直接訪談個案來收集相關臨床訊息，使用認知功能篩選量表中文版（Cognitive Abilities Screening Instrument, Chinese version；CCASI）來評估個案之認知功能，同時進行相關之生理檢查，以CCASI得分經年齡與教育程度做校正來界定認知功能是否障礙。結果：共收集80位個案，平均年齡67.9歲。認知功能障礙組有24位（佔30%，平均71.0歲）。與認知正常組互相比較，發現認知功能障礙組之社會功能表現（Global Assessment of Function Scale，GAF=60.1±11.0；Community Psychiatric Rating Scale，CPRS=10.4±4.9）顯著較低於認知正常組（GAF=71.9±9.5；CPRS=15.9±4.1），但就血壓、身體質量指數（body mass index）、初次發病年齡、發病頻率、精神症狀等變項，二組並無差異。結論：目前就醫中之年齡高於60歲之雙相情感障礙症患者，有30%可能已出現認知功能障礙（顯著高於一般老年人），而合併社會功能差則為其臨床特徵。

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