Monotherapy or Add-on Lamotrigine for Bipolar Disorder

10.29478/TJP.200406.0008

Shu-I Wu；Chun-Kai Fang；Kuang-Hsien Wu；Shen-Ing Liu

Lamotrigine ； bipolar disorder ； mood stabilizer

台灣精神醫學

18卷2期（2004 / 06 / 01）

142 - 146

英文

Objective: We report the treatment of two patients with bipolar disorder with lamotrigine, an anticonvulsant with mood-stabilizing and antidepressant properties. Case reports: One patient with bipolar II disorder with rapid cycling and one with treatment-refractory bipolar I disorder each responded well to lamotrigine 50 mg/day and remained cycle-free during 'two years' follow-ups. Conclusion: Lamotrigine appears to be useful as a mood stabilizer in patients with rapid-cycling and treatment-refractory bipolar disorder who have responded poorly to first-line agents.