Depressive Mood and Cognition in the Elderly Schizophrenic Patients

老年精神分裂症病人之憂鬱情緒與認知症狀

10.29478/TJP.200812.0006

黃照(Chao Huang)；張亞林(Ya-Lin Zhang)；林玉財(Yu-Tsai Lin)

老年精神分裂症 ； 臨床症狀 ； 認知功能 ； 角色功能 ； elderly schizophrenia ； clinical symptoms ； cognition ； role function

台灣精神醫學

22卷4期（2008 / 12 / 01）

296 - 306

英文

目的：探討慢性病房中老年精神分裂症患者之症狀、角色功能和性別、憂鬱、認知功能與的相關現況。方法：本次調查採用橫斷面現況研究方法進行現況調查。在北部一綜合醫院慢性病房中進行，在2007年6-9月間符合DSM-IV-TR診斷精神分裂症的60歲或以上的病患為對象，共計52人（其中男性31人，平均年齡65.7歲）。個案接受面對面的會談和測驗，研究工具有：基本人口學資料、精神分裂病史、正性及負性症狀量表(PANSS)、流行病學中心憂鬱量表(CES-D)、簡易認知狀態測驗(MMSE)、褚氏日常生活功能評量表(ADLRS)、社區自主能力測驗(CST)及功能總體評定量表(GAF)。結果：憂鬱與PANSS正性症狀、一般精神病症狀及總分有相關，認知缺損與PANSS負性症狀、ADLRS中自我照顧能力得分及總分有相關，女性患者有較多的正性症狀與已婚者。結論：慢性病房中的老年精神分裂症患者的憂鬱與認知缺損有不同的相關因素，其原因需進一步大規模追蹤研究其相關因素。

Objectives: To investigate gender difference and correlation between depression, cognition and symptoms, role function of chronic ward elderly schizophrenic patients. Methods: With the cross-sectional study method, we investigated all the hospitalized elderly schizophrenia patients in one northern psychiatric chronic ward from June to September 2007. All the subjects were matched the diagnostic criteria of schizophrenia in DSM-IV-TR and age 60 years old or above. We enrolled 52 subjects (31 males, mean age=65.7 years). We collected information of demographic data and illness history. Positive and Negative Syndrome Scale, Center for Epidemiological Studies Depression Scale, Mini-Mental Status Examination, Activities of Daily Living Rating Scale for Psychiatric Patients, Community Self-Sufficiency Test, and the General Assessment of Functioning Scale were administered. Results: Depression was found to be related to positive, general psychopathology, and total symptoms severity. Cognitive impairment was found to be related to negative symptoms, ADLRS independent subscale and total score. Female patients was found to have more being married and positive symptoms. Conclusions: In chronic ward elderly schizophrenic patients, depression and cognitive impairment had different related factors. Further large scale, longitudinal studies are needed to understand the causes of these findings.

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