题名

Add-on Theta Burst Stimulation for Treatment-resistant Depression with Migraine

并列篇名

陣發型磁波刺激對難治型憂鬱症合併偏頭痛之治療

DOI

10.29478/TJP.200812.0009

作者

林志光(Chih-Kuang Lin)；黃英儒(Ying-Zu Huang)；劉嘉逸(Chia-Yih Liu)；洪錦益(Ching-I Hung)；陳柔賢(Rou-Shayn Chen)；蕭美君(Mei-Chun Hsiao)

关键词

重覆經顱磁刺激 ； 陣發型磁波刺激 ； 難治型憂鬱症 ； 偏頭痛 ； repetitive transcranial magnetic stimulation rTMS ； theta burst stimulation TBS ； treatment-resistant depression ； migraine

期刊名称

台灣精神醫學

卷期/出版年月

22卷4期（2008 / 12 / 01）

页次

322 - 326

内容语文

英文
中文摘要

目的：以重覆經顱磁刺激治療神經與精神疾病，正引起越愈來愈多的注意。一種新興形式的經顱磁刺激，稱做陣發型磁波刺激，最近正積極發展研究中。先前文獻並無相關個案報告提到關於陣發型磁波刺激對於難治型憂鬱症合併偏頭痛的治療效果。病例報告：我們以兩個星期的陣發型磁波刺激療程，治療一名四十六歲罹患難治型憂鬱症與偏頭痛的女性患者，在治療之後，其偏頭痛有顯著的改善(71%)，憂鬱症狀也達到部分緩解(25%)。結論：本文提出陣發型磁波刺激，對於憂鬱症患者合併偏頭痛可能有潛在性的療效。
英文摘要

Background: Growing interest in using of repetitive transcranial magnetic stimulation (rTMS) to treat neurological and psychiatric diseases is emerging. A novel form of rTMS called theta burst stimulation (TBS) has been recently developed. To our knowledge, little information has been reported on TBS to treat migraine. Case report: We gave a two-week course of TBS to a 46-year-old woman with migraine and treatment-resistant depression. The patient remained on her ongoing antidepressant during TBS therapy. After the treatment, her depression was improved. The scores of the Hamilton Rating Scale for Depression (HAMD), the Hamilton Rating Scale for Anxiety (HAMA) and Beck Depression Inventory (BDI) were decreased from the pre-treatment baselines by 25%, 21% and 19%, respectively. According to her formal migraine diary, the intensity and frequency of her migraine attacks were improved by 25% and 71%, respectively. Conclusion: This case report suggests that rTMS (and specifically TBS) might provide a potential nonpharmacologic therapy for patients with both depression and migraine.
主题分类 醫藥衛生 > 社會醫學
参考文献
  1. Ben-Shachar D,Gazawi H,Riboyad-Levin J,Klein E(1999).Chronic repetitive transcranial magnetic stimulation alters beta-adrenergic and 5-HT2 receptor characteristics in rat brain.Brain Res,816,78-83.
  2. Breslau N,Davis GC,Schultz LR,Peterson EL(1994).Migraine and major depression: a longitudinal study.Headache,34,387-393.
  3. Breslau N,Lipton RB,Stewart WF,Schultz LR,Welch KM(2003).Comorbidity of migraine and depression: Investigating potential etiology and prognosis.Neurology,60,1308-1312.
  4. Brighina F,Piazza A,Vitello G(2004).rTMS of the prefrontal cortex in the treatment of chronic migraine: a pilot study.J Neurol Sci,227,67-71.
  5. Garcia-Tom M,Mayo1 A,Arnillas H(2001).Modest adjunctive benefit with transcranial magnetic stimulation in medication-resistant depression.J Affect Disord,64,271-275.
  6. Huang YZ,Edwards MJ,Rounis E,Bhatia KP,Rothwell SC(2005).Theta burst stimulation of the human motor cortex.Neuron,45,201-206.
  7. Juang KD,Wang SJ,Fuh JL,Lu SR,Su TP(2000).Comorbidity of depressive and anxiety disorders in chronic daily headache and its subtypes.Headache,40,818-23.
  8. Merikangas KR,Risch NJ,Merikangas JR,Weissman MM,Kidd KK(1988).Migraine and depression: association and familial transmission.Psychiatry Res,22,119-129.
  9. O''Reardon JP,Fontecha JF,Cristancho MA,Newman S(2007).Unexpected reduction in migraine and psychogenic headaches following rTMS treatment for major depression: a report of two cases.CNS Spectr,12,921-925.
  10. Su TP,Huang CC,Wei IH(2005).Add-on rTMS for medication-resistant depression: a randomized, double- blind, sham-controlled that in Chinese patients.J Glin Psychiatry,66,930-937.
print cancel