Discrepancy of Wechsler Adult Intelligence Scale-Ⅲ Scores in Recently Detoxified Han Taiwanese Male Alcoholic Patients

台灣漢族男性酒精依賴病人於近期解毒後施測第三版魏氏成人智力量表的分項差距

10.29478/TJP.201009.0005

黃名琪(Ming-Chi Huang)；陳俊興(Chun-Hsin Chen)；邱彥龍(Yen-Long Chiou)；林式穀(Shih-Ku Lin)

魏氏成人智力量表第三版WAIS-Ⅲ ； 神經心理學 ； 酒精依賴 ； 分項差距 ； Wechsler Adult Intelligence Scale Ⅲ ； neuropsychology ； alcohol dependence ； discrepancy

台灣精神醫學

24卷3期（2010 / 09 / 01）

191 - 200

英文

Objectives: Chronic alcohol consumption can lead to neuropsychological impairment. The Wechsler Adult Intelligence Scale-Ⅲ (WAIS-Ⅲ) provides sub-domain information of intellectual functioning. In this study we aimed to investigate the abnormal discrepancies in WAIS-Ⅲ among Han Taiwanese male patients with alcohol dependence. Methods: Following one-week of alcohol detoxification treatment, male inpatients fulfilling the DSM-IV criteria of alcohol dependence were assessed using WAIS-Ⅲ. We defined abnormal discrepancy as the score difference between verbal intelligent quotient (VIQ) and performance intelligent quotient (PIQ), verbal comprehension index (VCI) and perceptual organization index (POI), and working memory index (WMI) and processing speed index (PSI) greater than 15, 17, and 21, respectively. We compared differences of demographic and clinical variables between patients with (discrepancy group) or without (non-discrepancy group) abnormal VIQ/PIQ or VCI/POI discrepancies. Results: Thirty- three male patients (mean age: 40.8±7.4 years) completed the WAIS-Ⅲ evaluation. Compared to the norm, alcoholic subjects were found to have lower PIQ scores, due to significantly poorer POI (p＜0.05) and PSI (p＜0.05) performance. There were abnormal VIQ/PIQ, VCI/POI, or WMI/PSI discrepancies in 10 (30.3%), 8 (24.2%), and 9 (27.3%) patients, respectively. The POI subtest scores, including picture completion, block design, and picture arrangement, were significantly lower (p＜0.05) in the discrepancy group (N=12) than non-discrepancy group (N=21). Both groups did not differ significantly in demographic or drinking-related variables. Conclusion: Compared to Taiwanese norm, our recently detoxified alcoholic males were likely to have lower PIQ. They also showed higher frequencies of abnormal VIQ/PIQ, VCI/POI, or WMI/PSI discrepancies as defined by the study.

Objectives: Chronic alcohol consumption can lead to neuropsychological impairment. The Wechsler Adult Intelligence Scale-Ⅲ (WAIS-Ⅲ) provides sub-domain information of intellectual functioning. In this study we aimed to investigate the abnormal discrepancies in WAIS-Ⅲ among Han Taiwanese male patients with alcohol dependence. Methods: Following one-week of alcohol detoxification treatment, male inpatients fulfilling the DSM-IV criteria of alcohol dependence were assessed using WAIS-Ⅲ. We defined abnormal discrepancy as the score difference between verbal intelligent quotient (VIQ) and performance intelligent quotient (PIQ), verbal comprehension index (VCI) and perceptual organization index (POI), and working memory index (WMI) and processing speed index (PSI) greater than 15, 17, and 21, respectively. We compared differences of demographic and clinical variables between patients with (discrepancy group) or without (non-discrepancy group) abnormal VIQ/PIQ or VCI/POI discrepancies. Results: Thirty- three male patients (mean age: 40.8±7.4 years) completed the WAIS-Ⅲ evaluation. Compared to the norm, alcoholic subjects were found to have lower PIQ scores, due to significantly poorer POI (p＜0.05) and PSI (p＜0.05) performance. There were abnormal VIQ/PIQ, VCI/POI, or WMI/PSI discrepancies in 10 (30.3%), 8 (24.2%), and 9 (27.3%) patients, respectively. The POI subtest scores, including picture completion, block design, and picture arrangement, were significantly lower (p＜0.05) in the discrepancy group (N=12) than non-discrepancy group (N=21). Both groups did not differ significantly in demographic or drinking-related variables. Conclusion: Compared to Taiwanese norm, our recently detoxified alcoholic males were likely to have lower PIQ. They also showed higher frequencies of abnormal VIQ/PIQ, VCI/POI, or WMI/PSI discrepancies as defined by the study.

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