| 题名 |
Risperidone-induced Leukopenia and Neutropenia |
| 并列篇名 |
Risperidone引起之低白血球症及低嗜中性球症 |
| DOI |
10.29478/TJP.201106.0010 |
| 作者 |
洪誌遠(Chih-Yuan Hung)；白雅美(Ya-Mei Bai) |
| 关键词 |
risperidone ； leucopenia ； neutropenia ； blood dyscrasias |
| 期刊名称 |
台灣精神醫學 |
| 卷期/出版年月 |
25卷2期（2011 / 06 / 01） |
| 页次 |
119 - 122 |
| 内容语文 |
英文 |
| 英文摘要 |
Background: Risperidone tends to have a lower risk of hematotoxicity. Here, we report a woman patient who developed risperidone-induced neutropenia. Case Report: A 64-year-old female patient with a diagnosis of bipolar disorder had received several antipsychotics previously, without a history of neutropenia or leucopenia. During a depressive episode with psychotic feature, she received risperidone 3.5 mg/day, lamotrigine 100 mg/day, and valproic acid 1,000 mg/day. Four weeks later, she had leukopenia (white blood cells [WBC]: 2900/mm^3) and neutropenia (1,131/mm^3) were noted in the regular laboratory test. Initially we suspected the lamotrigine was related to the neutropenia and discontinued it, and increased risperidone to 5 mg/day. Five days later, the neutrophil was further decreased to 1,015/mm^3, so we discontinued risperidone and switched risperidone to 5 mg/day to sulpiride 600 mg/day. Twelve days later, the WBC and differential count were returned to normal limits. Conclusion: This is the first report of risperidone-induced leukopenia and neutropenia in Taiwan. |
| 主题分类 |
醫藥衛生 >
社會醫學 |
| 参考文献 |
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