從腦傷病人之研究簡介語文材料中的單字處理歷程

Single Word Processing: Insights from Research on Brain-damaged Patients

吳嫻(Denise-Hsien Wu)

神經心理學 ； 音韻及拼字表徵 ； 語意及語法表徵 ； Wernicke-Lichtheim理論 ； 單一個案研究方法 ； Neuropsychology ； phonological and orthographic representations ； semantic and syntactic representations ； Wernicke-Lichtheim model ； single-case approach

應用心理研究

28期（2005 / 12 / 01）

119 - 140

繁體中文

認知神經科學研究的主要目標，在於闡釋人類大腦與行為之間的關係。在數種使用於此一領域的先進技術中，對於腦傷病人的研究具有長久的歷史，同時有其獨特的貢獻。某些腦傷病人的選擇性認知能力損傷，說明了和該作業相關的認知成分在功能上的獨立；兩個功能的雙重分離，更顯示其組成成分可能在行為功能和生理解剖上有不同的機制，以致其中一者單獨被腦傷所影響、而另一者則保存完整。在此文獻回顧中，首先簡介主要根據腦傷病人的失常行為所建構出的Wernicke-Lichtheim理論，並簡介對此傳統模式的評論和修正。本文接著將扼要地彙整神經心理學研究中，關於單一詞彙理解和產生歷程的實驗結果，同時對於部分支持詞彙具有獨立語法及語意表徵的證據，也作一簡要的討論。從此認知神經心理學的文獻回顧，我們不難發現：自Wernicke-Lichtheim理論提出之後，認知心理學家對於單一詞彙處理的各項功能以及所牽涉到的各種表徵，已有相當程度的瞭解。特別是在過去的二十幾年中，我們對於單一詞彙在口語及文字處理中所經過的歷程，也累積了相當豐富的知識。腦傷病人之正常和失常的行為表現，為許多在文獻中備受爭議的問題，點出了重要的研究方向，也為不同的假說提供了重要的佐證。此一領域應奠基於既有的知識，增加對語句層次之語言處理歷程的探討，以助完整之語言處理理論的發展。

The relationship between the brain and behaviors has been the focus of the research in cognitive neuroscience. In addition to linking different neural substrates to different cognitive abilities, studies in this field have provided valuable information on the mechanisms underlying human cognition. Compared with other advanced techniques employed in cognitive neuroscience, studies on brain-damaged patients have a long history and unique contribution to the field Specifically, the selective disruption of some task performance signifies the functional independence of a cognitive component subserving that task. The double dissociation between two functions further suggests the dissociation, possibly both functionally and anatomically, of two components. In the current overview, I first introduced the Wernicke-Lichtheim model, which is mainly constructed from brain-damaged patients' behavioral impairments I also reviewed the criticisms and modifications to this traditional view. Next, the neuropsychological findings regarding the processes involved in single word comprehension and production were summarized Evidence for separate lexical, syntactic, and semantic representations of a word was briefly discussed Among lexical representations, further segregation between input and output phonological and orthographic representations was demonstrated by case reports on single patient's selective deficits. The organization of semantic and grammatical representations was also proposed to account for patients' performance. From this overviwe of cognitive neuropsychological findings, we can conclude that our understanding of the functional organization of single word processing has progressed considerably since the Wernicke-Lichtheim model was proposed. In particular, considerable know ledge has accumulated concerning the organization of the systems involved in single word processing for both speech and writing during the past two decades. The data-collected have had important implications for various issues that have been greatly debated in the normal literature. More work is needed to elucidate the linguistic processing/representations at the sentence level and to contribute to the development of theories of language processing.

1. Albert, M. L.,Bear, D.(1957).Time to understand: a case study of word deafness with reference to the role of time in auditory comprehension.Brain,97,373-984.
2. Allen, M.,Badecker, W.(1999).Stem homograph and stem allomorphy: representing and processing inflected forms in a multilevel lexical system.Journal of Memory and Language,41,105-123.
3. Allport, D. A.,Funnell, E.(1981).Components of the mental lexicon.Philosophical Transactions of the Royal Society of London,B295,397-410.
4. Allport, D. A.,S. K. Newman,R. Epstein(Eds.)(1985).Current perspectives in dysphasia, 207-244.Edinburgh:Churchill Livingstone.
5. Auerbach, S., H.,Allard, T.,Naeser, M.,Alexander, M. P.,Albert, M. L.(1981).Pure word deafness: analysis of a case with bilateral lesions and a defect at the prephonemic level.Brain,105,271-300.
6. Badecker, W.,Caramazza A.(1991).Morphological composition in the lexical output system.Cognitive Neuropsychology,8,335-367.
7. Badecker, W.,Miozzo, M.,Zanuttini, R.(1995).The two-stage model of lexical retrieval: evidence from a case of anomia with selective preservation of grammatical gender.Cognition,57,193-216.
8. Beauvois, M. F.,Derouesne, J.(1981).Lexical or orthographic agraphia.Brain,104,21-49.
9. Beauvois, M.-F.(1982).Optic aphasia: a process of interaction between vision and language.Proceedings of the Royal Society,B298,35-47.
10. Beauvois, M.-F.,Saillant, B.,Meininger, V.,Lhermitte, F.(1978).Bilateral tactile aphasia: a tacto-verbal dysfunction.Brain,101,381-401.
11. Behrmann, M.,Bub, D.(1992).Surface dyslexia and dysgraphia: Dual routes, single lexicon.Cognitive Neuropsychology,9,209-251.
12. Berndt, R. S.,Caramazza, A.(1980).A redefinition of the syndrome of Broca`s aphasia: Implications for a neuropsychological model of language.Applied Psycholonguisitics,1,225-278.
13. Berndt, R. S.,Haendiges, A. N.,Burton, M. W.,Mitchum, C. C.(2002).Grammatical class and imageability in aphasic word production: their effects are independent.Journal of Neurolinguistics,15,353-371.
14. Berndt, R. S.,Mitchum, C.,Haendiges, A.(1996).Comprehension of reversible sentences in "agrammatism": a meta-analysis.Cognition,58,289-308.
15. Bird, H.,Franklin, S.,Howard, D.(2002).`Little words`-not really: Function and content words in normal and aphasic speech.Journal of Neurolinguistics,15,209-237.
16. Blumstein, S. E.,Baker, E.,Goodglass, H.(1977).Phonological factors in auditory comprehension in aphasia.Neuropsychologia,15,19-30.
17. Bub, D.,Kertesz, A.(1982).Evidence for lexico-graphic processing in a patient with preserved written over oral single word naming.Brain,105,687-717.
18. Bub, D.,Kertesz, A.(1982).Deep agraphia.Brain and Language,17,146-165.
19. Bybee, J. L.,M. Hammond,M. Noonan(Eds.)(1988).Theoretical morphology: Approaches in modern linguistic.San Diego, CA:Academic press.
20. Caramazza, A.,Berndt, R. S.(1978).Semantic and syntactic processes in aphasia: a review of the literature.Psychological Bulletin,85,898-918.
21. Caramazza, A.,Hillis, A. E.,Rapp, B. C.,Romani, C.(1990).The multiple semantic hypothesis: Multiple confusions?.Cognitive Neuropsychology,7,161-189.
22. Caramazza, A.,Miozzo, M.(1997).The relation between syntactic and honological knowledge in lexical access: evidence from the 'tip-of-the-tongue' henomenon.Cognition,64,309-343.
23. Caramazza, A.,Shelton, J. R.(1998).Domain specific knowledge systems in the brain: the animate-inanimate distinction.Journal of Cognitive Neuroscience,10,1-34.
24. Caramazza, A.,Zurif, E. B.(1976).Dissociation of algorithmic and heuristic processes in language comprehension: evidence from aphasia.Brain and Language,3,572-582.
25. Coltheart, M.,Funnell, E.,D. A. Allport,D. G. Mackay,W. Prinz,E. Scheerer(Eds.)(1987).Language perception and production: Relationships among listening, speaking, reading, and writing.London:Academic Press.
26. Coltheart, M.,Rastle, K.,Perry, C.,Langdon, R.,Ziegler, J.(2001).DRC: A dual route cascaded model of visual word recognition.Psychological Review,108,204-256.
27. D`Esposito, M.,Devinsky, O.(Eds.)(2004).Neurology of cognitive and behavioral disorders.Oxford:Oxford University Press.
28. Damasio, H.,M. T. Sarno(Ed.)(1998).Acquired aphasia.San Diego, CA:Academic Press, Inc.
29. Denes, G.,Semenza, C.(1975).Auditory modality-specific anomia: evidence from a case study of pure word deafness.Cortex,11,411.
30. Dronkers, N. F.(2000).The pursuit of brain-language relationships.Brain and Language,71,59-61.
31. Druks, J.(2002).Verbs and nouns: a review of the literature.Journal of Neurolinguistics,15,289-319.
32. Eggert G.(Translated)(1977).Wernicke`s works on aphasia.The Hague:Mouton.
33. Ellis, A. W.(1984).Introduction to Bramwell`s (1897) case of word meaning deafness.Cognitive Neuropsychology,1,245-258.
34. Farah M. J.,McClelland J. L.(1991).A computational model of semantic memory impairment: modality specificity and emergent category specificity.Journal of Experimental Psychology: General,120,339-357.
35. Farah, M.(2004).Visual Agnosia.Cambridge:MIT Press.
36. Farah, M. J.,Wallace, M. A.(1992).Semantically-bounded anomia: Implications for the neural implementatjion of naming.Neuropsychologia,30,609-621.
37. Frackowiak, R.,Friston, K. J.,Frith, C.,Dolan, R.,Mazziotta, J.(Eds.)(1997).Human brain function.San Diego:Academic Press.
38. Franklin, S.,Howard, D.,Patterson, K.(1994).Abstract word meaning deafness.Cognitive Neuropsycholinguistics,11,1-34.
39. Franklin, S.,Turner, J.,Lambon-Ralph, M. A.,Morris, J.,Bailey, P. J.(1996).A distinctive case of word meaning deafness?.Neuropsychology,13,1139-1162.
40. Friedman, R. B.,Hadley, J. A.(1992).Letter-by-letter surface alexia.Cognitive Neuropsychology,9,185-208.
41. Funnell, E.(1987).Morphological errors in acquired dyslexia: a case of mistaken identity.Quarterly Journal of Experimental Psychology,39,497-539.
42. Garrett, M. F.,G. Blanken,J. Dittman,H. Grim,J. Marshall,C. Wallesch(Eds.)(1993).Linguistic disorders and pathologies.Berlin, Germany:de Gruyter.
43. Goodglass, H.(1993).Understanding aphasia.San Diego, CA, US:Academic Press, Inc.
44. Goodglass, H.,Klein, B.,Carey, P.,Jones, K.(1996).Specific semantic word categories in aphasia.Cortex,2,74-89.
45. Griffiths, T. D.,Rees, A.,Green, G. G. R.(1995).Disorders of human complex sound processing.Neurocase,5,365-378.
46. Hall, D. A.,Riddoch, M. J.(1997).Word meaning deafness: spelling words that are not understood.Cognitive Neuropsychology,14,1131-1164.
47. Hart, J.,Berndt, R. S.,Caramazza, A.(1985).Category-specific naming deficit following cerebral infarction.Nature,316,439-440.
48. Heilman, K.,Valenstein, E.(Eds.)(2003).Clinical Neuropsychology.Oxford:Oxford University Press.
49. Hillis, A. E.,B. Rapp(Ed.)(2001).The handbook of cognitive neuropsychology: What deficits reveal about the human mind.Philadelphia, PA:Psychology Press/Taylor & Francis.
50. Hillis, A. E.,Caramazza, A.(1995).Converging evidence for the interaction of semantic and sublexical phonological information in accessing lexical representations for spoken output.Cognitive Neuropsychology,12,187-227.
51. Hillis, A. E.,Caramazza, A.(1991).Mechanisms for accessing lexical representations for output: Evidence from a category-specific semantic deficit.Brain and Language,40,106-144.
52. Hillis, A. E.,Rapp, B. C.,Romani, C.,Caramazza, A.(1990).Selective impairment of semantics in lexical processing.Cognitive Neuropsychology,7,191-243.
53. Hillis, A.E.,Boatman, D.,Hart, J.,Gordon, B.(1999).Making sense out of jargon: a neurolinguistic and computational account of jargon aphasia.Neurology,53,1813-1824.
54. Howard, D.,Franklin, S.(1988).Missing the meaning: A cognitive neuropsychological study of processing of words by an aphasic patient.Boston, MA:M.I.T. Press.
55. Howard, D.,Franklin, S.,G. Vallar,T. Shallice(1990).Neuropsychological impairments of short-term memory.Cambridge, England:Cambridge University Press.
56. Joanisse, M. F.,Seidenberg, M. S.(1999).Impairments in verb morphology after brain injury: a connectionist model.Proceedings of the Nationall Academy of Science, U.S.A.,96,7592-7597.
57. Kohn, S. E.,Friedman, R. B.(1986).Word-meaning deafness: a phonological-semantic dissociation.Cognitive Neuropsychology,3,291-308.
58. Levelt, W. J. M.,Roelofs, A.,Meyer, A. S.(1999).A theory of lexical access in speech production.Behavioral Brain Sciences,22,1-75.
59. Lhermitte, F.,Beauvois, M.-F.(1973).A visual-speech disconnexion syndrome: report of a case with optic aphasia, agnosic alexia and colour agnosia.Brain,97,695-714.
60. Lichtheim, L.(1985).On aphasia.Brain,7,433-484.
61. Linebarger, M.,A. Caramazza(Ed.)(1990).Cognitive neuropsychology and neurolinguistics: Advances in models of cognitive function and impairment.Hillsdale, NJ:Lawrence Erlbaum.
62. Linebarger, M.,Schwartz, M.,Saffran, E.(1983).Sensitivity to grammatical structure in so-called agrammatic aphasics.Cognition,13,361-392.
63. Lukatela, G.,Turvey, M. T.(1994).Visual lexical access is initially phonological: I. Evidence from associative priming by words, homophones, and pseudohomophones.Journal of Experimental Psychology: General,123,107-128.
64. Martin, N.,Saffran, E. M.(2002).The relationship of input and output phonological processing: an evaluation of models and evidence to support them.Aphasiology,16,107-150.
65. Martin, N,Saffran, E. M.(1992).A computational account of deep dysphasia: evidence from a single case study.Brain and Language,43,240-274.
66. Martin, R. C.,Lesch, M. F.,Bartha, M. C.(1999).Independence of input and output phonology in word processing and short-term memory.Journal of Memory and Language,41,3-29.
67. Miceli, G.,Silveri, M. C.,Villa, G.,Caramazza, A.(1984).On the basis for the agrammatics` difficulty in producing main verbs.Cortex,20,207-220.
68. Mohr, J. P.,Pessin, M. S.,Finkelstein, S.,Funkenstein, H. H.,Duncan, G. W.,Davis K. R.(1978).Broca aphasia: pathologic and clinical.Neurology,28,311-324.
69. Nickels, L.,B. Rapp(Ed.)(2001).The handbook of cognitive neuropsychology: What deficits reveal about the human mind.Philadelphia, PA:Psychology Press/Taylor & Francis.
70. Nickels, L.,Howard, D.,Best, W.(1997).Fractionating the articulatory loop: dissociations and associations in phonological recoding in aphasia.Brain and Language,56,161-182.
71. Park, N.,Martin, R. C.(2001).Reading versus writing: evidence for the dissociation of input and output graphemic lexicons.Poster presented at Cognitive Neuroscience Society Eighth Annual Meeting,New York, U.S.A.:
72. Patterson, K.(2002).A double dissociation but a single mechanism? Further neuropsychological evidence on the past-tense debate.Presented at Cog. Neurosci. Soc. Meeting, 9th,San Fransicso:
73. Patterson, K.,Lambon-Ralph, M. A.,Hodges, J. R.,McClelland, J. L.(2001).Deficits in irregular past-tense verb morphology associated with degraded semantic knowledge.Neuropsychologia,39,709-724.
74. Poeppel, D.(2001).Pure word deafness and the bilateral processing of the speech code.Cognitive Science,25,679-693.
75. Rapp B,Caramazza A.(2002).Selective difficulties with spoken nouns and written verbs: a single case study.Journal of Neurolinguistics,15,373-402.
76. Rapp, B. C.,Benzing, L.,Caramazza, A.(1997).The autonomy of lexical orthographic representations.Cognitive Neuropsychology,14,71-104.
77. Rapp, B. C.,Caramazza, A.(1997).The modality specific organization of lexical categories: evidence from impaired spoken and written sentence production.Brain and Language,56,248-286.
78. Riddoch, M. J.,Humphreys, G. W.,Coltheart, M.,Funnell, E.(1988).Semantic systems or system? Neuropsychological evidence re-examined.Cognitive Neuropsychology,5,3-25.
79. Rorden, C.,Karnath, H. O.(2004).Using human brain lesions to infer function: a relic from a past era in the fMRI age?.Nature Reviews Neuroscience,5,813-819.
80. Rumelhart, D. E.,McClelland, J. L.,J. McClelland,D. Rumelhart(Eds.)(1986).Parallel Distributed Processing: Explorations in the Microstructure of Cognition.Cambridge, MA:M.I.T. Press.
81. Saffran, E. M.,Schwartz, M.(1988)."Agrammtic" comprehension it`s not: Alternatives and implications.Aphasiology,2,389-394.
82. Sartori, G.,Job, R.(1988).The oyster with four legs: a neuropsychological study on the interaction of visual and semantic information.Cognitive Neuropsychology,5,105-132.
83. Schwartz, M. F.,Saffran, E. M.,Marin, O. S.(1980).The word order problem in agrammatism: I. Comprehension.Brain and Language,10,249-262.
84. Selnes, O. A.,Knopman, D. S.,Niccum, N.,Rubens, A.B.,Larson, D.(1983).Computed tomographic scan correlates of auditory comprehension deficits in aphasia: a prospective recovery study.Annals of Neurology,13,558-566.
85. Shallice, T.(1988).From neuropsychology to mental structure.New York, NY:Cambridge University Press.
86. Shallice, T.,M. Coltheart,G. Sartori,R. Job(Eds.)(1987).The cognitive neuropsychology of language.London:Erlbaum.
87. Shapiro, K,Shelton, J,Caramazza, A.(2000).Grammatical class in lexical production and morphological processing: evidence from a case of fluent aphasia.Cognitive Neuropsychology,17,665-682.
88. Shelton, J. R.,Caramazza, A.(1999).Deficits in lexical and semantic processing: implications for models of normal language.Psychonomic Bulletin & Review,6,5-27.
89. Shelton, J. R.,Caramazza, A.,B. Rapp(Ed.)(2001).The handbook of cognitive neuropsychology: What deficits reveal about the human mind.Philadelphia, PA:Psychology Press/Taylor & Francis.
90. Shelton, J. R.,Weinrich, M.(1997).Further evidence of a dissociation between output phonological and orthographic lexicons: a case study.Cognitive Neuropsychology,14,105-129.
91. Silveri, M. C.,Gainotti, G.(1988).Interaction between vision and language in category-specific impairment.Cognitive Neuropsychology,5,677-709.
92. Squire, L. R.(1987).Memory and Brain.New York:Oxford University Press.
93. Tanaka, Y.,Yamadori, A.,Mori, E.(1987).Pure word deafness following bilateral lesions: a psychophysical analysis.Brain,110,381-403.
94. Tsapkini, K,Jarema, G,Kehayia E.(2002).A morphological processing deficit in verbs but not in nouns: a case study in a highly inflected language.Journal of Neurolingistics,15,265-288.
95. Tyler, L. K.,Randall, B.,Marslen-Wilson, W. D.(2002).Phonology and neuropsychology of the English past tense.Neuropsychologia,40,1154-1166.
96. Ullman, M. T.,Corkin, S.,Coppola, M.,Hickok, G.,Growdon, J. H.(1997).A neural dissociation within language: evidence that the mental dictionary is part of declarative memory, and that grammatical rules are processed by the procedural system.Journal of Cognitive Neuroscience,6,266-276.
97. Van Orden, G.C.(1987).A ROWS is a ROSE: Spelling, sound, and reading.Memory and Cognition,15,181-198.
98. Vigliocco, G.,Vinson, D. P.,Martin, R. C.,Garrett, M. F.(1999).Is "count" and "mass" information available when the noun is not? An investigation of tip of the tongue states and anomia.Journal of Memory and Language,40,534-558.
99. Wang, E.,Peach, R. K.,Xu, Y.,Schneck, M.,Manry, C.(2000).Perception of dynamic acoustic patterns by an individual with unilateral verbal auditory agnosia.Brain and Language,73,442-445.
100. Warrington, E. K.,McCarthy, R.(1987).Categories of knowledge: further fractionation and an attempted integration.Brain,100,1273-1296.
101. Warrington, E. K.,Shallice, T.(1984).Category-specific semantic impairments.Brain,107,829-853.
102. Wernicke, C.(1874).Der aphasische symptomenkomplex.Breslau:Cohn Weigert.
103. Wise, R. J. S.,Scott, S. K.,Blank, S. C.,Mummery, C. J.,Murphy, K.,Warburton, E. A.(2001).Separate neural subsystems within `Wernicke`s area`.Brain,124,83-95.
104. Zingeser, L. B.,Berndt, R. S.(1990).Retrieval of nouns and verbs in agrammatism and anomia.Brain and Language,39,14-32.
105. Zingeser, L. B.,Berndt, R. S.(1988).Grammatical class and context effects in a case of pure anomia: implications for models of language production.Cognitive Neuropsychology,5,473-516.