题名

照護一位肝癌末期病人接受臨床試驗失敗之護理經驗

并列篇名

The Nursing Experience of a Patient with Advanced stage of Hepatocellular Carcinoma after Failing the Clinical Trial

DOI

10.6540/NTJN.201809_20(2).0012

作者

李佳欣(Chia-Hsin Lee);郭淑柳(Shu-Liu Guo);盧芝菁(Chih-Ching Lu)

关键词

肝癌末期 ; 臨床試驗失敗 ; 癌症疼痛 ; 體液容積過量 ; 無望感 ; cancer patients with advanced stage of hepatocellular carcinoma (HCC) ; clinical trial failure ; cancer pain ; fluid overload-ascites and limb lymphedema ; hopelessness

期刊名称

新臺北護理期刊

卷期/出版年月

20卷2期(2018 / 09 / 01)

页次

135 - 145

内容语文

繁體中文

中文摘要

本文探討一位肝癌末期病人接受藥物臨床試驗失敗後,承受生、心理衝擊之護理過程,個案於2015年9月29日至10月28日住院治療,運用Gordon十一項健康功能評估型態進行整體性評估,藉由直接觀察、會談、身體評估等方式收集資料,歸納確立因疾病惡化,個案有癌症疼痛、體液容積過量及下肢淋巴水腫與無望感等健康問題。提供合宜護理照護改善個案症狀困擾,包含疼痛處置-藥物及非藥物方法,精油按摩及下肢淋巴按摩等措施。此外,提供心理支持,整合安寧團隊共同照護,執行個案的生命回顧,體悟生命意義與價值,與家人及重要朋友進行最後道別,最後完成個案臨終返家心願及善終目的。期望藉此接受臨床試驗失敗的護理經驗分享,提供護理人員臨床照護之參考。

英文摘要

The article was to describe the nursing experience of a patient with advanced stage of hepatocellular carcinoma (HCC), who suffered from a high level of physical and psychological distress after failing cancer clinical trial from 29 September to 28 October, 2015. Gordon’s 11 healthy functional patterns were used to assess his health problems through observation, interviewing, and physical examination. Problems included cancer pain, fluid overload-ascites and limb lymphedema, and hopelessness due to the rapid progressive disease. We provided nursing care to improve his symptom distress, including analgesics, non-pharmacological pain management, aromatherapy with massage, and decongestive therapy of limb lymphedema. Moreover, psychological supports were provided, including integrating the hospice and palliative shared care team, doing patient's life review, understanding the meaning of life and the value of life, and termination-goodbyes to family members and important friends. Finally, his last wish with hospice-dying at home and the purpose of having a Good Dying were completed. We expected to provide this nursing experience in caring for patients who fail the clinical trial as a reference for nurses.

主题分类 醫藥衛生 > 預防保健與衛生學
醫藥衛生 > 社會醫學
参考文献
  1. 林雅萍,羅樺鈴,巫怡翎,曾斐琳(2015)。照顧一位肝癌末期病人之護理經驗。長庚護理,26(2),203-213。
    連結:
  2. 莊玉華,戴秀珍,許秀萍,蔡麗紅(2016)。照護一位血液透析病人合併不寧腿症候群之護理經驗。長庚護理,27(1),132-143。
    連結:
  3. Ali , B.,Al-Wabel , N.A.,Shams, S.,Ahamad, A.,Khan S.A.,Anwar, F.(2015).Essential oils used in aromatherapy: A systemic review.Asian Pacific Journal of Tropical Biomedicine,5(8),601-611.
  4. Cancer Research UK. (2017) Phases of clinical trials. Avialable at: http://www.cancerresearchuk.org/about-cancer/find-a-clinical-trial/what-clinical-trials-are/phases-of-clinical-trials
  5. Carlson, L. E.,Bultz, B. D.,Morris, D.G.(2005).Individualized quality of life, standardized quality of life, and distress in patients undergoing a phase I trial of the novel therapeutic.Health and Quality of Life Outcomes,3,7-17.
  6. Carr, B.I.(2004).Hepatocellular Carcinoma: Current Management and Future Trends.Gastroenterology,127(5),S218-S224.
  7. Dave, V.,Yadav, S.(2013).Aromatherapy for relive.International Journal of Research and Development in Pharmacy and Life Sciences,2(3),398-403.
  8. Ford, A.C.,Talley, N.J.,Spiegel, B.M.,Foxx-Orenstein, A.E.,Schiller, L.,Quigley, E.M.,Moayyedi, P.(2008).Effect of fibre, antispasmodics, and peppermint oil in the treatment of irritable bowel syndrome: systematic review and meta-analysis.BMJ,337,a2313-a2323.
  9. Goodman, Z.D.(2007).Neoplasms of the liver.Moderm Patholgy,20,S49-S60.
  10. Gross, A.H.,Cromwell, J.,Fonteyn, M.,Matulonis, U.A.,Hayman, L.L.(2013).Hopelessness and complementary therapy use in patients with ovarian cancer.Cancer Nursing,36(4),256-264.
  11. Kelly, C.,Ghazi, F.,Caldwell, K.(2002).Psychological distress of cancer and clinical trial participantion: a review of the literature.European Journal of Cancer care,11,6-15.
  12. Koulivand,P. H.,Ghadiri, M. K.,Gorji, A.(2013).Lavender and the Nervous System.Evidence-Based Complementary and Alternative Medicine,2013,681304.
  13. Lin, M.H.,Wu, P.Y.,Tsai, S.T.,Lin, C.L.,Chen, T.W.,Hwang, S.J.(2004).Hospice palliative care for patients with hepatocellular carcinoma in Taiwan.Palliative Medicine,18,93-99.
  14. Mahipal, A.,Nguyen, D.(2014).Risks and benefits of Phase 1 clinical trial participation.Cancer Control,21(3),193-199.
  15. Moore, S.(2001).A need to try everything: patient participation in phase I trials.Journal of Advanced Nursing,33(6),699-854.
  16. National Comprehensive Cancer Network. (2017). NCCN Clinical Practice Guidelines in Oncology-Adult Cancer Pain. Version 2.2017. Available at: https://www.nccn.org/professionals/physician_gls/pdf/pain.pdf
  17. National Institutes of Health-National Cancer Institute. (2017). What are Clinical Trials? Available at: https://www.cancer.gov/about-cancer/treatment/clinical-trials/what-are-trials
  18. Potosek, J.,Curry, M.,Buss, M.,Chittenden, E.(2014).Integration of Palliative Care in End-Stage Liver Disease and Liver Transplantation.Journal of Palliative Medicine,17(11),1271-1277.
  19. Ripamonti, C.(ed.),Bruera, E.(ed.)(2002).Gastrointestinal symptoms in advanced cancer patients.New York:Oxford University Press, Inc.
  20. Shomura1, M.,Kagawa, T.,Okabe, H.,Shiraishi, K.,Hirose, S.,Arase, Y.,Tsuruya, K.,Takahira, S.,Mine, T.(2016).Longitudinal alterations in health-related quality of life and its impact on the clinical course of patients with advanced hepatocellular carcinoma receiving sorafenib treatment.BMC Cancer,16,878-886.
  21. Siegel, R.L.,Miller, K.D.,Jemal, A.(2017).Cancer Statistics, 2017.CA: A Cancer Journal of Clinicians,67,7-30.
  22. Sritoomma, N.,Moyle, W.,Cooke, M.,O'Dwyer, S.(2014).The effectiveness of Swedish massage with aromatic ginger oil in treating chronic low back pain in older adults: a randomized controlled trial.Complementary Therapies in Medicine,22(1),26-33.
  23. Such, J., & Runyon, B.A. (2017). Pathogenesis of ascites in patients with cirrhosis. Available at: https://www.uptodate.com/contents/pathogenesis-of-ascites-in-patients-with-cirrhosis?source=see_link§ionName=PORTAL%20HYPERTENSION&anchor=H2#H2
  24. Sun, V.C.Y.,Sarna, L.(2008).Symptom management in hepatocellulat carcinoma.Clinical Journal of Oncology Nursing,12(5),759-766.
  25. Venâncio, A. M.,Onofre, A.S.,Lira, A.F.,Alves, P.B.,Blank, A.F.,Antoniolli, A.R.,Marchioro, M.,Estevam, C.dos S.,de Araujo, B.S.(2011).Chemical composition, acute toxicity, and antinociceptive activity of the essential oil of a plant breeding cultivar of basil (Ocimum basilicum L.)..Planta Med,77,825-829.
  26. Warmenhoven, F.,Lucassen, P.,Vermandere, M.,Aertgeerts, Bert,Weel, C.V.,Vissers, K.,Prins, J .(2016).Life is still worth living’: a pilot exploration of self-reported resources of palliative care patients.BMC Fam Pract,17,52-52.
  27. 王蓉君,陳恆德(2011)。台灣臨床試驗發展之沿革。臺灣醫界雜誌,54(7),51-55。
  28. 洪玉純,施秀鈴,潘雪幸(2014)。運用善終理念照顧一位卵巢癌末期病人的護理經驗。源遠護理,8(2),63-69。
  29. 黃惠美,郭素真,王靜慧,張議文,周幸生(2012)。建立成人癌症病人疼痛非藥物處置之臨床照護指引。榮總護理,29(2),145-158。
  30. 衛生福利部(2017)‧104年死因統計年報‧2017年6月8日取自http://dep.mohw.gov.tw/DOS/lp-1777-113.html
  31. 蘇清菁,陳玉敏(2009)。無望感之概念分析。長庚護理,20(4),456-462。
被引用次数
  1. 蔡瑋瑋,林玉菁,蔡瑋瑋,林玉菁(2021)。照護一位肝癌末期病人之護理經驗。長庚護理,32(2),112-123。
  2. 廖婉君,黃敦頌,林俊昌(2023)。一位42歲男性接受兩階段肝切除術後發燒表現。台灣專科護理師學刊,10(1),63-69。