麩醯胺酸補充劑對有氧舞蹈後一氧化氮與同半胱胺酸的影響

Effects of L-Glutamine Supplementation on Nitric Oxide and Homocysteine after Aerobic Dancing

10.5297/ser.1901.006

唐存愷(Tswen-Kei Tang)；傅正思(Cheng-Sze Fu)；何應志(Ying-Chih Ho)；陳文詮(Wen-Chyuan Chen)；陳聰毅(Tsung-I Chen)；蔡佈曦(Pu-Hsi Tsai)

耐力運動 ； 心血管健康 ； 血糖 ； endurance exercise ； cardiovascular health ； blood glucose

大專體育學刊

19卷1期（2017 / 03 / 31）

87 - 98

繁體中文;英文

麩醯胺酸對心血管健康的影響，是因為麩醯胺酸與精胺酸和一氧化氮生成有關，本研究目的在探討補充麩醯胺酸對未受運動訓練的女學生，從事有氧舞蹈後對恢復期血中一氧化氮 (nitric oxide, NO) 與同半胱胺酸的影響。以14 位健康的女子大學生為對象，隨機分成兩組分別服用補充劑，一組補充安慰劑，一組補充L- 麩醯胺酸，補充劑量皆為每公斤體重0.1 公克，然後進行單次有氧舞蹈運動，連續運動2 小時，運動強度為55 ~ 75% 最大心跳率。每位受試者在運動前及運動後0、1、2 小時，採血以測量一氧化氮 (NOx, NO_2^- +NO_3^-)、同半胱胺酸、血糖、胰島素、高密度脂蛋白膽固醇 (high-density lipoprotein cholesterol, HDL-C)、低密度脂蛋白膽固醇 (low-density lipoprotein cholesterol, LDL-C)、三酸甘油酯及總膽固醇。研究結果顯示：運動後血中一氧化氮、胰島素、HDL-C、LDL-C、三酸甘油酯及總膽固醇在兩組間並沒有顯著差異。而補充麩醯胺酸組會增加運動後血中同半胱胺酸及葡萄糖濃度。因此麩醯胺酸可能可以幫助增加運動後恢復期同半胱胺酸及血糖。而目前並沒有足夠證據顯示補充麩醯胺酸能增加耐力運動恢復期的一氧化氮。本研究結論為單次補充麩醯胺酸並不能增加耐力運動2 小時恢復期血中一氧化氮含量，且沒有改善心血管健康指標的效果。

The L-glutamine has been studied in cardiovascular health, because of its association with the L-arginine- NO cascade. This study aimed to investigate the effects of L-glutamine supplementation on acute plasma nitric oxide (NO) and homocysteine responses during recovery after aerobic dancing in untrained female students. Fourteen healthy female university students were randomly divided into two groups and received either placebo or L-glutamine at 0.1 g/kg-wt. Then the students were performed a single bout of aerobic dancing at an estimated speed corresponding to the 55 ~ 75% HRmax for 2 hours. Blood samples from each student were collected before exercise, and 0, 1 and 2 hours after exercise. The concentrations of NOx (NO_2^- + NO_3^-), homocysteine, glucose, insulin, HDL-C (high-density lipoprotein cholesterol), LDL-C (low-density lipoprotein cholesterol), triglycerol, and total cholesterol in blood were examined. The results showed that no differences in the levels of NOx, insulin, HDL-C, LDL-C, triglycerol, and total cholesterol between the groups were observed at any time points. However, the concentrations of homocysteine and glucose were significantly higher in the glutamine group compared to that in the placebo group at 0-hour following exercise. The L-glutamine supplementation could increase homocysteine and glucose concentrations during post-exercise recovery period, but there is insufficient evidence to support the view that plasma NO levels are being increased by L-glutamine supplementation after endurance exercise. In conclusion, acute ingestion of L-glutamine does not increase the NO synthesis and does not improve the cardiovascular risk factors during 2 hours recovery period following endurance exercise.

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