耐力運動後補充麩醯胺酸對恢復期血液能量代謝物的影響

Effect of Glutamine Supplementation on Blood Energy Substrate During Recovery Period After Endurance Exercise

10.5297/ser.201809_20(3).0007

何應志(Ying-Chih Ho)；李淑玲(Shu-Lin Lee)；蔡佈曦(Pu-Hsi Tsai)；陳文詮(Wen-Chyuan Chen)；傅正思(Cheng-Sze Fu)

葡萄糖 ； 甘油 ； 介白素-6 ； glucose ； glycerol ； IL-6

大專體育學刊

20卷3期（2018 / 09 / 30）

279 - 293

繁體中文;英文

本研究目的在觀察耐力運動後麩醯胺酸的補充，對恢復期血液能量代謝物之影響。以7位具運動訓練之運動員為受試者，實驗採用雙盲交叉設計，每位受試者必須進行1小時75% VO_(2max)跑步機運動後，分別補充0.1 g/kg bw之左旋—麩醯胺酸(L-glutamine)或安慰劑（烴丙基甲基纖維素），於運動前、後第0、15、30、45、60、90與120分鐘進行靜脈採血，並測量血液葡萄糖、胰島素、甘油和游離脂肪酸濃度。研究結果發現麩醯胺酸對恢復期血液中葡萄糖及胰島素濃度並無明顯之影響；但在脂解代謝物，補充組血液中甘油濃度於恢復期第60、90與120分鐘時明顯低於安慰劑組，此外，補充組血液中介白素-6 (interleukin-6, IL-6)濃度，在運動後明顯高於安慰劑組。本研究結論是耐力運動後補充麩醯胺酸抑制體內脂解作用，同時增強IL-6上升的反應。

This study aimed to investigate the effect of glutamine supplementation on blood energy substrate levels during the recovery period following endurance exercise. Seven healthy male athletes were randomized into two trials: Placebo or Glutamine (0.1 g/kg bw), and performed a single bout of exercise at an estimated speed corresponding to the 75% maximal oxygen uptake (VO_(2max)) for 60 minutes. Plasma glucose, insulin, glycerol and free fatty acid concentrations of each athlete were measured before exercise, and 0, 15, 30, 45, 60, 90, and 120 minutes after exercise. Results showed no differences in glucose and insulin levels between the trials. Compared to the placebo trial, glycerol concentration in the glutamine trials was significantly lower at 60, 90, and 120-min during post-exercise recovery, and interleukin-6 (IL-6) concentration was significantly higher during the recovery period. We concluded that glutamine supplementation inhibits the lipolysis and induce higher IL-6 response during the recovery period following endurance exercise in young male adults.

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