题名

台灣南部即將入伍役男之血清睪固酮與勃起功能障礙相關性調查

并列篇名

A Survey of Testosterone Levels and Erectile Dysfunction of Men Conscripted into the Military in Southern Taiwan

DOI

10.6784/FJS.201010.0029

作者

趙建剛(Jian-Kang Chao);林燕卿(Yen-Chin Lin);顧艶秋(Yan-Chiou Ku);蔡景宏(Ching-Hong Tsai);劉江華(Jiang-Hwa Liu);奚明德(Ming-Der Shi)

关键词

勃起功能障礙 ; 睪固酮 ; 身體質量指數 ; Body Mass Index ; Erectile Dysfunction ; Testosterone

期刊名称

台灣性學學刊

卷期/出版年月

16卷2期(2010 / 10 / 01)

页次

29 - 41

内容语文

繁體中文

中文摘要

目的:本研究以日常生活模式、身體質量指數及血清睪固酮濃度,找出勃起功能障礙與正常控制組之差異性,並進一步探討日常生活模式、身體質量指數及血清睪固酮濃度與勃起功能障礙之關係。方法:本研究採取兵役體檢之役男182名爲施測對象,除血液檢驗外,另加測驗血清睪固酮檢查,並分別施測國際性功能障礙指標及一般基本問卷,並針對各項因素做一評估,其中屬於勃起功能障礙患者共31名,正常控制組共151名。結果:本研究以SPSS統計方法,針對二組做統計分析,二組之間並無年齡、教育程度上之差異。以邏輯式迴歸分析調整抽菸及喝酒兩變項後,顯示在目前肥胖及血清睪固酮濃度偏低等兩分項之間有顯著之差異。結論:預防勃起功能障礙,我們應針對我們可以改變的生活型態去做調整,適度的飲食及飲酒、抽菸的控制,控制體重在正常體位,如睪固酮濃度偏低,我們可補充適量之睪固酮,如此也可減少勃起功能障礙的發生。

英文摘要

Objective: The purpose of this study was to examine the difference between the group with erectile dysfunction and the normal control groups through three dimensions: daily lifestyle, body mass index and serum testosterone concentration level, and further explored the associations of erectile function with daily lifestyle, body mass index and serum testosterone concentration level. Methods: Data were obtained and assessed from a baseline survey of 182 young adult military conscripts, with their demographic data, blood test, serum testosterone test, and responses to the IIEF questionnaire. There were 31 subjects with erectile dysfunction in the experimental group, while there were a total of 151 in the normal control groups. Results: SPSS was used to analyze the data of the two groups. There were no significant differences in age and education level between the two groups. Logistic regression analysis was used for analysis of all the variables. There was a significant difference between obesity and lower testosterone concentration, alcohol consumption and lower testosterone concentration. Conclusion: For the prevention of erectile dysfunction, we should focus on the adjustment to the lifestyle, which we can change-such as moderate eating, drinking and smoking control, weight control. The proper amount of testosterone supplement may reduce the incidence of erectile dysfunction.

主题分类 社會科學 > 教育學
社會科學 > 社會學
社會科學 > 社會學
参考文献
  1. Althof, S. E.(2002).Quality of life and erectile dysfunction.Urology,59,803-810.
  2. American Association of Clinical Endocrinologists(2002).Medical guidelines for clinical practice for the evaluation and treatment of hypogonadism in adult male patients- 2002 update.Endocrine Practice,8,440-456.
  3. Amiaz, R., Seidman, S. N.(2008).Testosterone and depression in men.Current Opinion Endocrinology Diabetes and Obesity,15,278-283.
  4. Araujo, A. B.,Travison, T. G.,Ganz, P.,Chiu,G. R.,Kupelian, V.,Rosen, R. C.(2009).Erectile dysfunction and mortality.The Journal of Sexual Medicine,6,2445-2454.
  5. Aytac, I. A.,McKinlay, J. B.,Krane, R. J.(1999).The likely worldwide increase in erectile dysfunction between 1995 and 2025 and some possible policy consequences.British Journal of Urology International,84,50-56.
  6. Barrett-Connor, E.(1992).Lower endogenous androgen levels and dyslipidemia in men with non-insulin-dependent diabetes mellitus.Annal of Internal Medicine,117,807-811.
  7. Barrett-Connor, E.,Khaw, K. T.(1988).Endogenous sex hormones and cardiovascular disease in men. A prospective population-based study.Circulation,78,539-545.
  8. Buvat, J. ,Lemaire, A.(1997).Endocrine screening in 1,022 men with erectile dysfunction: clinical significance and cost-effective strategy.The Journal of Urology,158,1764-1767.
  9. Campion, J. M.,Maricic, M. J.(2003).Osteoporosis in men.American Family Physician,67,1521-1526.
  10. Chiang, H. S.(2001).Epidemiology of hypogonadism in Asia.The Aging Male,4(Suppl.1),125-131.
  11. Esposito, K.,Giugliano, F.,Di Palo, C.,Giugliano, G.,Marfella R.,D''Andrea, F.(2004).Effect of lifestyle changes on erectile dysfunction in obese men.The Journal of American Medical Association,291,2978-2984.
  12. Ferreiros, E. R.,Boissonnet, C. P.,Pizarro, R.,Merletti, P. F. G.,Corrado, G.,Cagide, A.(1999).Independent prognostic value of elevated C-reactive protein in unstable angina.Circulation,100,1958-1963.
  13. Gapstur, S. M.,Gann, P. H.,Kopp, P.,Colangelo, L.,Longcope, C.,Liu, K.(2002).Serum androgen concentration in young men: a longitudinal analysis of association with age, obesity, and race. The CARDIA male hormone study..Cancer Epidemiology Biomarker and Prevention,11,1041-1047.
  14. Gazzaruso, C.,Solerte, S. B.,Pujia, A.,Coppola, A.,Vezzoli, M.,Salvucci, F.(2008).Erectile dysfunction as a predictor of cardiovascular events and death in diabetic patients with angiographically proven asymptomatic coronary artery disease: A potential protective role for statins and 5-phosphodiesterase inhibitors.Journal of American College of Cardiology,51,2040-2044.
  15. Gray, P. B.,Singh, A. B.,Woodhouse, L. J.,Storer, T. M.,Casaburi, R.,Dzekov, J.(2005).Dose-dependent effects of testosterone on sexual function, mood, and visuospatial cognition in older men.Journal of Clinical Endocrinology & Metabolism,90,3838-3846.
  16. Inman, B. A.,Sauver, J. L.,Jacobson, D. J.,McGree, M. E.,Nehra, A.,Lieber, M. M.(2009).A population-based, longitudinal study of erectile dysfunction and future coronary artery disease.Mayo Clinical Proceeding,84,108-113.
  17. Jain, P.,Rademaker, A. W.,McVary, K. T.(2000).Testosterone supplementation for erectile dysfunction: results of a meta-analysis.The Journal of Urology,164,371-375.
  18. Johnson, S. D.,Phelps, D. L.,Cottler, L. B.(2004).The association of sexual dysfunction and substance use among a community epidemiological sample.Archives of Sexual Behavior,33(1),55-63.
  19. Kelleher, S.,Conway, A. J.,Handelsman, D.J.(2004).Blood testosterone threshold for androgen deficiency symptoms.Journal of Clinical Endocrinology & Metabolism,89,3813-3817.
  20. Kleinman, K. P.,Feldman, H. A.,Johannes, C.B.,Derby, C. A.,McKinlay, J. B.(2000).A new surrogate variable for erectile dysfunction status in the Massachusetts Male Aging Study.Journal of Clinicial Epidemiology,53(1),71-78.
  21. Kontoleon, P. E.,Anastasiou-Nana, M. I.,Papapetrou, P. D.,Alexopoulos, G.,Ktenas, V.,Rapti, A. C.(2003).Hormonal profile in patients with congestive heart failure.International Journal of Cardiology,87,179-183.
  22. Kulkarni, S. R.,Ravindra, K. P.,Dhume, C. Y.,Rataboli, P.,Rodrigues, E.(2009).Levels of plasma testosterone, antioxidants and oxidative stress in alcoholic patients attending de-addiction centre.Biology and Medicine,1(4),11-20.
  23. Mallis, D.,Moisidis, K.,Kirana, P. S.,Papaharitou, S.,Simos, G.,Hatzichristou, D.(2006).Moderate and severe erectile dysfunction equally affects life satisfaction.The Journal of Sexual Medicine,3,442-449.
  24. Millett, C.,Wen, L. M.,Rissel, C.,Smith, A.,Richters, J.,Grulich, A.(2006).Smoking and erectile dysfunction: findings from a representative sample of Australian men.Tobacco Control,15,136-139.
  25. Moffat, S. D.,Zonderman, A. B.,Metter, E. J.,Kawas, C.,Blackman, M. R.,Harman, S.M.(2004).Free testosterone and risk for Alzheimer disease in older men.Neurology,62,188-193.
  26. Morales, A.,Buvat, J.,Gooren, L. J.,Guay, A.T.,Kaufman, J. M.,Tan, H. M.(2004).Endocrine aspects of sexual dysfunction in men.The Journal of Sexual Medicine,1,69-81.
  27. Nilsson, P.,Moller, L.,Solkad, K.(1995).Adverse effects of psychosocial stress on gonadal function and insulin levels in middle aged males.Journal of Internal Medicine,237,479-486.
  28. Phillips, G. B.,Jing, T. Y.,Resnick, L. M.,Barbagallo, M.,Laragh, J. H.,Sealey, J. E.(1993).Sex hormones and hemostatic risk factors for coronary heart disease in men with hypertension.Journal of Hypertension,11,699-702.
  29. Rosen, R. C.,Cappelleri, J. C.,Smith, M. D.,Lipsky, J.,Pena, B. M.(1999).Development and evaluation of an abridged 5-item version of the International Index of Erectile Function (IIEF 5) as a diagnostic tool for erectile dysfunction.International Journal of Impotence Research,11,319-326.
  30. Rosen, R.,Fisher,W.,Eardley, I.,Niederberger,C.,Nadel, A.,Sand, M.(2004).The multinational Men's Attitude to Life Events and sexuality (MALES) study, 1: prevalence of erectile dysfunction related health concerns in the general population.Current Medical Research Opinion,20,607-617.
  31. Schiavi, R. C.,Rehman, J.(1995).Sexuality and aging.The Urologic ClinicsNorth America,22,711-726.
  32. Schiavi, R. C.,White, D.,Mandeli, J.,Levine, A. C.(1997).Effect of testosterone administration on sexual behavior and mood in men with erectile dysfunction.Archives of Sexual Behavior,26,231-241.
  33. Schouten, B. W.,Bohnen, A. M.,Bosch, J. L.,Bernsen, R. M.,Deckers, J. W.,Dohle, G.R.(2008).Erectile dysfunction prospectively associated with cardiovascular disease in the Dutch general population: Results from the Krimpen Study.International Journal of Impotence Research,20,92-99.
  34. Seidman, S.,Roose, S. P.(2006).The sexual effects of testosterone replacement in depressed men: Randomized, placebo-controlled clinical trial.Journal of Sex& Marital Therapy,32,267-273.
  35. Svartberg, J.,von Muhlen, D.,Schirmer, H.,Barrett-Connor, E.,Sundfjord, J.,Jorde,R.(2004).Association of endogenous testosterone with blood pressure and left ventricular mass in men. The Tromso Study..European Journal of Endocrinology,150(1),65-71.
  36. Thompson, I. M.,Tangen, C. M.,Goodman, P.J.,Probstfield, J. L.,Moinpour, C. M.,Coltman, C. A.(2005).Erectile dysfunction and subsequent cardiovascular disease.The Journal of the American Medical Association,294,2996-3002.
  37. Traish, A. M.,Goldsteinc, I.,Kim, N. N.(2007).Testosterone and erectile function: From basic research to a new clinical paradigm for managing men with androgen insufficiency and erectile dysfunction.Europen Urology,52(1),54-70.
  38. Travison, T. G.,Shabsigh, R.,Araujo, A. B.,Kupelian, V.,O''Donnell, A. B.,McKinlay, J. B.(2007).The natural progression. and remission of erectile dysfunction: Results from the Massachusetts Male Aging Study.The Journal of Urology,177,241-246.
  39. Välimäki, M. J.,Härkönen, M.,Eriksson, C. J.,Ylikahri, R.H.(1984).Sex hormones and adrenocortical steroids in men acutely intoxicated with ethanol.Alcohol,1(1),89-93.
  40. Van Pottelbergh, I.,Braeckman, L.,De Bacquer, D.(2003).Differential contribution of testosterone and estradiol in the determination of cholesterol and lipoprotein profile in healthy middle-aged men.Atherosclerosis,166,95-102.
  41. Venkat, K. K.,Arora, M. M.,Singh, P.,Desai,M.,Khatkhatay, I.(2009).Effect of alcohol consumption on bone mineral density and hormonal parameters in physically active male soldiers.Bone,45(3),449-454.
  42. Vgontzas, A. N.,Papanicolaou, D. A.,Bixler, E.O.,Kales, A.,Tyson, K.,Chrousos, G. P.(1997).Elevation of plasma cytokines in disorders of excessive daytime sleepiness: role of sleep disturbance and obesity.Journal of Clinical Endocrinology & Metabolism,82,1313-1316.
  43. Williams, R. H. (Ed.),Foster, D. W. (Ed.),Kronenberg, H.M. (Ed.),Larsen, P. R. (Ed.),Wilson, J. M. (Ed.)(1998).Williams textbook of endocrinology.Philadelphia:Saunders.
  44. 江漢聲、林蕙瑛、邱志偉(2002)。威而剛服用後性愛生活滿意度分析。台北市醫師公會會刊,46(3),14-18。