A Preliminary Psychosocial Study of Parkinson's Patients After Fetal Tissue Transplantation

胚胎移植對巴金森氏症病患心理及社會層面影響初探

唐福瑩(Fu-In Tang)；許樹珍(Shuh-Jen Sheu)；陳清惠(Ching-Huey Chen)；王昀(Yun Wang)；林欣榮(Shinn-Zong Lin)

巴金森氏症 ； 胚胎移植 ； 心理社會 ； 護理 ； Parkinson's disease ； fetal transplantation ； psychosocial ； nursing

The Journal of Nursing Research

10卷1期（2002 / 03 / 01）

1 - 14

英文

利用胚胎黑質細胞治療巴金森氏症，是目前可能有效的方式。但移植成果之評估大多以組織學、放射學及身體檢查爲主，卻很少有研究指出病患在移植後心與社會調適之改變。因此，本研究利用訪談及問卷調查法，針對台灣地區進行胚胎移植之六位巴金森氏症病患，進行身、心、社會整體評估之探討‘初步研究結果顯示，在生理功能上每人的改善程度不一，但“走路”的進步是大多數病患最滿意的部分，相對而言，“穿衣”，及“寫字”的進步最不滿意，在心理層次上，六位病患均主訴有尤慮感受，其他尚包括害怕，矛盾及身體心像改變。而在社會層次上，則爲與配偶的關係變差及社會互動減少。本研究同時發現對胚胎移植知識的不足與上述結果有關。因此，根據本結果而提出的護理因應措施，特別強調在病患及家屬對胚胎移植治療之認知與瞭解上，幫助病患有更佳的調適。

A novel and promising approach currently available is the grafting of fetal nigra tissues into the brain of a Parkinson’s patient. However, the degree of success for such treatment has mainly been evaluated by histological, radiological and physical assessments, with little or no attention paid to its effects on the patient’s psychosocial status. In order to provide a more comprehensive profile, a survey was conducted using questionnaires and interviews to examine the physio-psycho-social progress of six Parkinson’s patients who underwent fetal tissue grafting in Taiwan. Results indicated that the physiological effects varied among patients. Noticeably an improvement in walking was the most gratifying, but progress in dressing and writing ability seemed disappointing. From the psychological point of view, depression was commonly felt by patients. Other feelings included fear, ambivalence, and change in body image. In addition, all six patients found that their relationship with spouse became worse; they also reduced social interaction to the minimum. From the findings, we also noticed that inadequate knowledge contributed to part of the results. Therefore, some nursing suggestions especially educating the patients and family about the facts and outcome of fetal tissue transplantation are highly recommended. These may help Parkinson’s patients adjust better after undergoing this novel treatment.

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