Supportive Care Needs Trajectories in Patients With Advanced Non-Small-Cell Lung Cancer Receiving Chemotherapy: A Longitudinal Study

10.1097/jnr.0000000000000556

Chun-Ju YEN；Hsin-Tien HSU；Hsiu-Fen HSIEH；Ying-Ju CHEN；Ming-Shyan HUANG；Pei-Chao LIN

chemotherapy ； lung cancer ； supportive care needs ； trajectory

The Journal of Nursing Research

31卷3期（2023 / 06 / 01）

1 - 8

英文

Background: The supportive care needs trajectories in patients with advanced non-small-cell lung cancer (NSCLC) during chemotherapy and the related factors have yet to be explored or addressed in the literature. Purpose: This study was designed to investigate supportive care needs trajectories in patients with advanced NSCLC receiving chemotherapy and the association between the sociodemographic and disease characteristics of these patients over the four cycles of chemotherapy. Methods: For this longitudinal study, 95 patients with advanced NSCLC were recruited using convenience sampling at a medical center in Taiwan. The supportive care needs of the participants were assessed in each of the four chemotherapy cycles using the Needs Evaluation Questionnaire-Chinese version (NEQ-C) with 23 dichotomous items on the day before and the seventh day after the end of each cycle. Group-based trajectory modeling was applied to identify the classes of supportive care needs trajectories, whereas chi-square tests were used to examine the factors related to these classes. Results: Seventy-one participants completed all eight questionnaire sessions across the four cycles. The mean NEQ-C scores for these participants ranged between 14.4 and 14.6. Three classes of supportive care needs trajectories (low, moderate, and high) were identified for the entire NEQ-C and for each domain. Marital status was found to be associated with the classes of trajectories related to supportive care and assistance/care needs, spouse as the primary caregiver was found to be associated with the classes of trajectories related to information needs, and educational level was found to be associated with the classes of trajectories related to psychoemotional support needs. Conclusions: The results of this study indicate that marital status and spouse as primary caregiver relate significantly to supportive care needs trajectories in patients with advanced NSCLC during chemotherapy. Healthcare professionals should provide continuous, tailored supportive care interventions that address the needs of patients and their spouses/partners.

1. Chiu, H.-Y.,Lin, Y.-H.,Wang, C.-C.,Chen, W.-Y.,Chang, H.-C.,Lin, M.-C.(2016)。Exploration the care needs of post-chemotherapy lung cancer patients and related factors。The Journal of Nursing，63(3)，62-72。
   連結：
2. Zhang, T.,He, H.,Liu, Q.,Lv, X.,Song, Y.,Hong, J.(2019).Supportive care needs of patients with lung cancer in Mainland China: A cross-sectional study.The Journal of Nursing Research,27(6),e52.
   連結：
3. American Cancer Society. (2019). What is lung cancer? https://www.cancer.org/cancer/lung-cancer/about/what-is.html
4. Bonacchi, A.,Miccinesi, G.,Galli, S.,Primi, C.,Chiesi, F.,Lippi, D.,Muraca, M.,Toccafondi, A.(2016).Use of the needs evaluation questionnaire with cancer outpatients.Support Care in Cancer,24(8),3507-3515.
5. Cochrane, A.,Woods, S.,Dunne, S.,Gallagher, P.(2022).Unmet supportive care needs associated with quality of life for people with lung cancer: A systematic review of the evidence 2007-2020.European Journal of Cancer Care,31(1),e13525.
6. Doubova, S. V.,Pérez-Cuevas, R.(2020).Supportive care needs and quality of care of patients with lung cancer in Mexico: A cross-sectional study.European Journal of Oncology Nursing,49,101857.
7. Giuliani, M. E.,Milne, R. A.,Puts, M.,Sampson, L. R.,Kwan, J. Y.,Le, L. W.,Alibhai, S. M.,Howell, D.,Abdelmutti, N.,Liu, G.,Papadakos, J.,Catton, P.,Jones, J.(2016).The prevalence and nature of supportive care needs in lung cancer patients.Current Oncology,23(4),258-265.
8. Harrison, J. D.,Young, J. M.,Price, M. A.,Butow, P. N.,Solomon, M. J.(2009).What are the unmet supportive care needs of people with cancer? A systematic review.Support Care in Cancer,17(8),1117-1128.
9. Huang, Z. P.,Cheng, H. L.,Loh, S. Y.,Cheng, K. K. F.(2020).Functional status, supportive care needs, and health-related quality of life in advanced lung cancer patients aged 50 and older.Asia-Pacific Journal of Oncology Nursing,7(2),151-160.
10. Jones, B.,Nagin, D.,Roeder, K.(2001).A SAS procedure based on mixture models for estimating developmental trajectories.Sociological Methods & Research,29,374-393.
11. Kao, S.-F.,Sung, Y.-C.,Hwang, Y.-F.,Chang, F.-Y.,Chang, Y.-J.(2013)。A preliminary study on lung cancer patients care needs and related factors。VGH Nursing，20(4)，329-339。
12. Kyte, K.,Ekstedt, M.,Rustoen, T.,Oksholm, T.(2019).Longing to get back on track: Patients' experiences and supportive care needs after lung cancer surgery.Journal of Clinical Nursing,28(9-10),1546-1554.
13. Lam, W. W.,Law, W. L.,Poon, J. T.,Fong, D.,Girgis, A.,Fielding, R.(2016).A longitudinal study of supportive care needs among Chinese patients awaiting colorectal cancer surgery.Psychooncology,25(5),496-505.
14. Lam, W. W.,Tsang, J.,Yeo, W.,Suen, J.,Ho, W. M.,Yau, T. K.,Soong, I.,Wong, K. Y.,Kwong, A.,Suen, D.,Sze, W. K.,Ng, A. W.,Girgis, A.,Fielding, R.(2014).The evolution of supportive care needs trajectories in women with advanced breast cancer during the 12 months following diagnosis.Support Care in Cancer,22(3),635-644.
15. Lee, T. Y.,Susanti, H. D.,Hung, K. C.,Yang, S. Y.,Fang, H. F.,Tsai, J. R.,Chiou, J. F.,Chung, M. H.(2021).Health care needs of elderly patients with lung, liver, or colon cancer in Taiwan.BMC Palliative Care,20(1),21.
16. Mazor, M. B.,Li, L.,Morillo, J.,Allen, O. S.,Wisnivesky, J. P.,Smith, C. B.(2022).Disparities in supportive care needs over time between racial and ethnic minority and non-minority patients with advanced lung cancer.Journal of Pain and Symptom Management,63(4),563-571.
17. McLouth, L. E.,Nightingale, C. L.,Levine, B. J.,Burris, J. L.,McDougall, J. A.,Lycan, T. W., Jr.,Gabbard, J.,Ruiz, J.,Farris, M.,Blackstock, A. W., Jr.,Grant, S. C.,Petty, W. J.,Weaver, K. E.(2021).Unmet care needs and financial hardship in patients with metastatic non-small-cell lung cancer on immunotherapy or chemoimmunotherapy in clinical practice.JCO Oncology Practice,17(8),e1110-e1119.
18. National Comprehensive Cancer Network. (2021). NCCN clinical practice guidelines in oncology (NCCN guidelines). Non-small cell lung cancer (version 2). https://www.nccn.org/professionals/physician_gls/pdf/nscl.pdf
19. Ni, X.,Lou, Y.,Hu, W.,Wang, H.,Xu, H.,Li, S.,Zhou, Y.,Ni, Y.(2022).Development of mobile-based self-management, support for patients with lung cancer: A stepwise approach.Nursing Open,9(3),1612-1624.
20. Pérez-Fortis, A.,Fleer, J.,Schroevers, M. J.,Alanís López, P.,Sánchez Sosa, J. J.,Eulenburg, C.,Ranchor, A. V.(2018).Course and predictors of supportive care needs among Mexican breast cancer patients: A longitudinal study.Psychooncology,27(9),2132-2140.
21. Petrillo, L. A.,Traeger, L. N.,Sommer, R. K.,Zhou, A. Z.,Temel, J. S.,Greer, J. A.(2021).Experience and supportive care needs of metastatic lung cancer survivors living with uncertainty: A brief qualitative report.Journal of Cancer Survivorship,15(3),386-391.
22. Reiser, V.,Rosenzweing, M.,Welsh, A.,Ren, D.,Usher, B.(2019).The Support, Education, and Advocacy (SEA) program of care for women with metastatic breast cancer: A nurse-led palliative care demonstration program.The American Journal of Hospice & Palliative Care,36(10),864-870.
23. Rossi, A.,Maio, M. D.(2016).Platinum-based chemotherapy in advanced non-small-cell lung cancer: Optimal number of treatment cycles.Expert Review of Anticancer Therapy,16(6),653-660.
24. Sung, H.,Ferlay, J.,Siegel, R. L.,Laversanne, M.,Soerjomataram, I.,Jemal, A.,Bray, F.(2021).Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.CA: A Cancer Journal for Clinicians,71(3),209-249.
25. Sussman, J.,Bainbridge, D.,Whelan, T. J.,Brazil, K.,Parpia, S.,Wiernikowski, J.,Schiff, S.,Rodin, G.,Sergeant, M.,Howell, D.(2018).Evaluation of a specialized oncology nursing supportive care intervention in newly diagnosed breast and colorectal cancer patients following surgery: A cluster randomized trial.Supportive Care in Cancer,26(5),1533-1541.
26. Toscano, A.,Blanchin, M.,Bourdon, M.,Bonnaud Antignac, A.,Sébille, V.(2020).Longitudinal associations between coping strategies, locus of control and health-related quality of life in patients with breast cancer or melanoma.Quality of Life Research,29(5),1271-1279.