從實證觀點探討癌症末期惡病質症候群之照護

Management of Cancer-Related Cachexia Syndrome: An Evidence-Based Approach

10.6880/TJON.201912_19(2).05

陳玥君(Yueh-Chun Chen)；王韋淯(Wei-Yu Wang)；陳鼎達(Ting-Tat Chan)；簡淑慧(Sui-Whi Jane)

癌症惡病質症候群 ； 症狀處置 ； 實證護理 ； cancer-related cachexia syndrome (CRCS) ； symptom management ； evidence-based nursing

腫瘤護理雜誌

19卷2期（2019 / 12 / 01）

67 - 76

繁體中文

惡病質是癌症病人最常見之症狀群，往往會導致病人體能衰退、治療效果減低、情緒困擾、社會活動受限、與照顧者關係緊張進而衝擊其生活品質，甚至加速死亡。從臨床觀點而言，能緩解此症狀群的處置或藥物治療有限，且處理上相當棘手，故很容易被腫瘤護理人員忽略。本文旨在透過實證文獻回顧癌症惡病質症候群的定義及診斷、病理機轉／相關導因、臨床評估、相關之實證處置及照護重點，期能增加臨床護理人員對於惡病質照護知能，進而提升對此族群之照護品質。

Cancer-related cachexia syndrome (CRCS) is the most common symptom for patients with cancer that tends to deteriorate their physical performance, compromise the therapeutic efficacy, impair their psychological, social functions and worsen the patient-caregiver relationship, leading to impacted quality of life and eventually accelerated death. From a clinical perspective, CRCS is still a thorny problem to resolve owing to the limited effective therapy or medications available for relieving this syndrome. As a result, CRCS is prone to be neglected by oncology nurses. The purpose of this paper is to literately review the definition, diagnosis, pathophysiological mechanisms/causes, clinical assessments, treatments, and related evidence-based medical modality and nursing care, enhancing the knowledge about CRCS for nurses to optimally improve the quality of care for this specific population.

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