探討去氧核糖核酸對小鼠老化抑制之影響作用

Effect of Deoxyribonucleic Acid on Aging Inhibition in Mice

10.30001/JIES.200212.0005

王銘富(Ming-Fu Wang)；林芳儀(Fang-Yi Lin)；張巧幸(Chiao-Hsing Chang)；吳青蓮(Ching-Lein Wu)

去氧核糖核酸 ； 老化 ； 老化促進小鼠 ； deoxyribonucleic acid ； ging ； senescence accelerated mice To whom correspondence should be addressed

美容科技學刊

1卷1期（2002 / 12 / 01）

55 - 72

繁體中文

The DNA damage cause aging and retrograde. The purposes of this study were to examine the effect of different dose deoxyribonucleic acid (DNA) supplement on aging inhibition in mice. Six-month-old senescence accelerated mice (SAMPS) were divided into three groups: casein diet group (control group) and casein diet supplemented with 0.2%, 0.5%DNA. After 12 weeks feeding, body weight, food intake and aging score were performed during the experiment. The results showed that food intake and body weight were no significantly among three groups. The aging score of control group was higher than the experimental group in 0.2% and 0.5%DNA (P＜0.05). In summary, we conclude the supply of DNA may improve aging score and delay the aging process.

The DNA damage cause aging and retrograde. The purposes of this study were to examine the effect of different dose deoxyribonucleic acid (DNA) supplement on aging inhibition in mice. Six-month-old senescence accelerated mice (SAMPS) were divided into three groups: casein diet group (control group) and casein diet supplemented with 0.2%, 0.5%DNA. After 12 weeks feeding, body weight, food intake and aging score were performed during the experiment. The results showed that food intake and body weight were no significantly among three groups. The aging score of control group was higher than the experimental group in 0.2% and 0.5%DNA (P＜0.05). In summary, we conclude the supply of DNA may improve aging score and delay the aging process.

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