蜜白花萃取物作為化妝品原料之研究

The Study of Radiqueen Extract on Cosmetic Application

10.30001/JIES.201209.0006

梁健成(Chien-Cheng Liang)；黃克峯(Ke-Feng Huang)

蜜白花萃取物 ； 抗氧化試驗 ； 體外美白試驗 ； Radiqueen extract ； Anti-oxidation ； In-vitro whitening assay

美容科技學刊

9卷3期（2012 / 09 / 01）

63 - 71

繁體中文

自1990年起，全球化妝品產業呈現快速成長的趨勢，尤以新興國家化妝品產業消費成長幅度最大，隨著經濟活動的熱絡，人們對美的需求與日俱增，肌膚保養品就是其中一項產品。在亞太地區，由於光照較充足，容易受紫外線照射，肌膚因而容易曬黑，所以美白產品為銷售的主力之一；除此之外，由於外在環境因素誘發老化肌膚產生，如何延緩肌膚老化產生，亦是關注的焦點。添加天然植物成分，讓肌膚呈現白皙與年輕化，是近年來肌膚保養品的另一項趨勢。本實驗研究擬以蜜白花萃取物，進行抗氧化與體外美白試驗，由實驗結果顯示，蜜白花萃取物有清除自由基與抑制酪胺酸酶活性作用，並可提供未來市場開發新產品添天然植物成分之參考依據。

The global cosmetic products have been presented the tendency of rapid growing from 1990, especially in developing countries, as the economic activities growing as the demand of beauty day by day on the skin cosmetic products. In Asia area, the whitening products are the most important of all cosmetics because of UV light of sunshine attacked the skin and resulted in sunburn. Besides, the science reports showed that outer surroundings brought out the aging of human skin because of the pollutants. Now, it is the concerning point to postpone the aging occurring. Recently, a tendency of skin cosmetic is that adding the natural material of plant extracts could whiten and rejuvenate the skin. We carried out the anti-oxidation and in-vitro whitening assay in the study of radiqueen extract. The results showed that radiqueen extract had anti-free radical ability and inhibited the activity of tyrosinase. The radiqueen extract will apply for using material of natural plants of cosmetic market in the future.

1. itis 智網 http://itisweb3.itis.org.tw/itisppt/client/slide.aspx?pre_id=1873
2. 中央氣象局 http://www.cwb.gov.tw/V7/observe/UVI/UVI.htm
3. 化妝保養品產業資訊 http://www.cosmetic.org.tw/page.php?id=1582
4. http://www.fda.gov.tw
5. Chang, Te-Sheng(2009).An Updated Review of Tyrosinase Inhibitors.Int J Mol Sci.,10(6),2440-2475.
6. Gillbro, J. M.,Olsson, M. J.(2011).The melanogenesis and mechanisms of skin-lightening agents--existing and new approaches.Int J Cosmet Sci.,33(3),210-21.
7. Hallivell, B.,Gunettdge, J. M.(1991).Free Radicals in Biology and Medicine.Oxford:Clarednon Press.
8. Harman, D.(1956).Aging: a theory based on free radicals and radiation chemistry.J Gerontology,11(3),298-300.
9. Kim, Y. J.,Uyama, H.(2005).Tyrosinase inhibitors from natural and synthetic sources: structure, inhibition mechanism and perspective for the future.Cell Mol Life Sci.,62(15),1707-23.
10. Kong, Yeon Hee,Jo, Youn Ock,Cho, Chang-Won,Son, Dongwook,Park, Soojin,Rho, Jeonghae,Choi, Sang Yoon(2008).Inhibitory effects of cinnamic acid on melanin biosynthesis in skin.Biol. Pharm. Bull,31(5),946-948.
11. Lu, Ching-You,Lee, Hsin-Chen,Fahn, Huei-Jyh,Wei, Yau-Huei(1999).Oxidative damage elicited by imbalance of free radical scavenging enzymes is associated with large-scale mtDNA deletions in aging human skin.Mutat Res,423(1-2),11-21.
12. Parvez, S.,Kang, M.,Chung, H. S.,Bae, H.(2007).Naturally occurring tyrosinase inhibitors: mechanism and applications in skin health, cosmetics and agriculture industries.Phytother Res.,21(9),805-16.
13. Wang, Kuo-Hsien,Lin, Rong-Dih,Hsu, Feng-Lin,Huang, Yen-Hua,Chang, Hsien-Chang,Huang, Ching-Yi,Lee, Mei-Hsien(2006).Cosmetic applications of selected traditional Chinese herbal medicines.Journal of Ethnopharmacology,106(3),353-359.
14. Yamaguchi, T.,Takamura, H.,Matoba, T.,Terao J.(1998).HPLC method for evaluation of the free radical-scavenging activity of foods by using 1, 1-diphenyl -2-picrylhydrazyl.Biosci. Biotechnol. Biochem,62(6),1201-1204.