Factors Affecting Risk of Cardiovascular Disease in Normotensive Sedentary Female Teens in Taiwan

血壓正常之靜態青少女心血管疾病危險因子相關性探討

李書芬(Shu-Fen Lee)；李志平(Chih-Ping Li)

Cardiovascular Disease ； Obesity ； Normotensive ； Hyperuricemia ； 心血管疾病 ； 肥胖 ； 正常血壓 ； 高尿酸血症

耕莘學報

19期（2021 / 12 / 01）

5 - 17

英文

Objectives: High-normal systolic blood pressure (SBP) in teenagers may raise the risk of cardiovascular disease (CVD) in adulthood. A better understanding is needed of teenager CVD risk factors. The intent of this study was to investigate and compare the risk factors found in the normotensive female teenager population that are known to cause CVD. Methods: Data was derived from 3,023 serum samples of freshmen during a health examination at a nursing college in Northern Taiwan from 2008 to 2011. We compared the participants' risk of CVD between four blood pressure groups: namely, the lowest, low, middle, and high normal systolic blood pressures (SBP). ANOVA, Chi-square, Person correlation, Multivariate linear, and logistic regressions were applied to analyze data. Results: All of the predictors related to cardiovascular risk factors showed low in the lowest-normal SBP group, and presented a significantly linear increase by level of SBP. Compared to the lowest-normal SBP group, the low-normal, middle-normal and high-normal SBP groups were more likely to have a high risk of obesity. In addition, the high-normal SBP group tended to higher risk of hyperuricemia compared to the lowest-normal SBP group. Conclusion: This study provides evidence of the correlation between obesity and hyperuricemia and CVD risk in the high-normal SBP group. To this end, BMI may be a precise predictor to increase blood pressure.

目的：青少年因不健康生活型態導致血液指標異常或肥胖，進而可能延續至成年人，導致罹患心血管疾病之人數逐年攀升。了解影響青少年心血管疾病的因素，以合適的健康促進計畫導入，以改變青少年的生活型態。本研究的目的是探討靜態青少女在正常血壓範圍之內與罹患心血管疾病之關係。方法：本研究採橫斷式相關研究法，以北部某教學醫院體檢中心之新生健康身體檢查資料庫進行分析，篩選15歲青少女健康檢查之資料，共計3023筆新生健檢資料。以單變量分析、趨勢分析、卡方檢定及多元迴歸分析等統計分析青少女正常血壓與罹患心血管疾病之關係。結果：青春後期到成年早期之間，血壓正常之青少女，若伴隨血液指標異常其發生代謝症候群或心血管疾病之風險隨之增高。青少女血液指標異常之盛行率隨血壓範圍升高有明顯上升趨勢。高血壓前期組相較其他三組在血液指標異常上呈現較高風險尤其是罹患肥胖症及高尿酸血症。結論：血液指標異常的早期診斷與防治是一項重要的健康推動，需要學校教師、校護、家長及醫療團隊等共同參與，以降低日後代謝症候群或心血管疾病發生之危險。