肛門生殖器濕疣之臨床表徵

Clinical Characteristics of Anogenital Wart

10.6200/TCMJ.2005.2.6.01

陳守堅(Shou-Chien Chen)；楊世仰(Shih-Yan Yang)；唐麗慧(Li-Hui Tang)；陳國東(Kow-Tong Chen)

人類乳突病毒 ； 肛門生殖器溼疣 ； 性傳染病 ； 人類免疫缺乏病毒 ； human papillomavirus ； anogenital wart ； sexually transmitted disease ； HIV

北市醫學雜誌

2卷6期（2005 / 06 / 01）

492 - 500

繁體中文

人類乳突病毒(human papillomavirus, HPV)是世界上最常見的性傳染病原之一，在一般人口群中約有1%的人受到感染，肛門生殖器溼疣(anogenital warts)則是人類乳突病毒感染常見的顯性表現(phenotypic)。某些HPV已被證實是女性子宮頸內皮病變及癌(cervical intraepithelial neoplasia and cancer)的原因之一。再方面目前國際上的研究發現感染性病的愛滋病患者，會增進愛滋病毒感染其性伴侶的危險性。女性愛滋病毒感染者合併感染HPV，與罹患子宮頸內皮病變及癌有極強的相關。據臺北市性病防治所2002至2004年門診資料顯示每年約有13%（5000-6000人／年）的門診病人是因肛門生殖器溼疣前往就醫。因此加強對肛門生殖器溼疣的瞭解是減少愛滋感染的重要策略之一。然而臺灣地區目前探討肛門生殖器溼疣的研究仍非常有限，本文回顧肛門生殖器溼疣的文獻，就肛門生殖器溼疣病因，臨床表現，診斷，治療作一整理，冀能提供這方面的知識給衛生醫療人員，以便作好性病及愛滋病的防治工作。

Human papillomaviruses (HPV) are amongst the most common sexually transmitted diseases (STD) in the world. Anogenital warts are a common phenotypic expression of human papillomaviruses which affect 1% of the population. Having sexually transmitted infections (STI) can increase the risk of passing HIV to a partner during sex. HIV-positive women have shown a strong and consistent relationship between co-infection with HIV and HPV, and cervical intraepithelial neoplasia (CIN). Between 2002 and 2004, 13% (5,000-6,000/year) of patients attending Taipei City STD clinic were diagnosed with anogenital warts. To have an understanding of anogenital warts is one the most important measures in reducing morbidity caused by HIV. However, there are very few papers on this topic. We have reviewed current knowledge of anogenital warts, including etiology, clinical manifestation, diagnosis and treatment, and draw attention to prevention and intervention efforts.