题名

Actinic Keratosis: A Case Report

并列篇名

日光角化症—病例報告

DOI

10.6200/TCMJ.202409_21(3).0007

作者

Da-Ming Liao(廖大銘);Chieh Chen(陳杰)

关键词

pre-cancerous squamous cell lesion ; actinic keratosis ; seborrheic keratosis ; ultraviolet radiation ; squamous cell carcinoma in situ ; 癌前鱗狀細胞病變 ; 日光角化症 ; 脂漏性角化症 ; 紫外線輻射 ; 鱗狀細胞原位癌

期刊名称

北市醫學雜誌

卷期/出版年月

21卷3期(2024 / 09 / 30)

页次

270 - 274

内容语文

英文;繁體中文

中文摘要

A 94-year-old woman came to the clinic because of itching and pain on the scalp and back. However, the lesion did not look like typical dermatitis but more like actinic keratosis - a precancerous lesion characterized by skin keratinization because of ultraviolet exposure, which may develop into squamous cell carcinoma. Primary physicians should be alert to this skin disease. Skin squamous cell carcinoma usually presents in the basal layer of the epidermis as early as adolescence. Thus, excessive sun exposure should be avoided starting from a younger age. Primary care physicians practicing in rural and fishing villages are likely to discover these skin lesions earlier and provide treatment or refer them to special clinics for further therapy. Primary care physicians can educate these villagers on how to prevent the disease from becoming skin cancer and teach them how to regularly follow up on the progress of skin lesions related to actinic keratosis.

英文摘要

一位94歲女性,因頭皮、背部搔癢、疼痛來醫院就診,但病灶看起來並不是典型的皮膚發炎,日光角化症是由皮膚角質化引起的皮膚癌前病變,可能發展成鱗狀細胞癌,基層醫師應該對這種皮膚病變有所警覺,日光角化症是由太陽光中的紫外線照射,引起的鱗狀細胞癌的早期皮膚病變,也是人類最常見的皮膚癌之一,皮膚鱗狀細胞癌通常早在青春期就出現在表皮的基底層;因此年輕時應避免過度日曬並適當的防曬,尤其是在農村、漁村執業的基層醫師,能夠及早發現這種皮膚發炎,並給予治療或轉診給皮膚專科醫師進一步治療,基層醫師可以衛教這些村民如何預防這種疾病發展成為皮膚癌,並且教導他們如何定期追蹤與日光角化症相關的皮膚病變的癌細胞發展。

主题分类 醫藥衛生 > 醫藥衛生綜合
参考文献
  1. Ackerman AB, Mones JM. Solar (actinic) keratosis is squamous cell carcinoma. Br J Dermatol 2006; 155(1): 9-22.
    連結:
  2. Newlands C, Currie R, Memon A, Whitaker S, Woolford T. Non-melanoma skin cancer: United Kingdom national multidisciplinary guidelines. J Laryngol Otol 2016; 130(Suppl 2): S125-32.
    連結:
  3. Dodds A, Chia A, Shumack S. Actinic keratosis: rationale and management. Dermatol Ther (Heidelb) 2014; 4(1): 11-31.
    連結:
  4. Lindqvist PG, Epstein E, Landin-Olsson M, et al. Avoidance of sun exposure is a risk factor for all-cause mortality: results from the Melanoma in Southern Sweden cohort. J Intern Med 2014; 276(1): 77-86.
    連結:
  5. Rongioletti F. Actinic keratoses: what classification is useful to predict the risk of progression? PRO s and cons. J Eur Acad Dermatol Venereol 2019; 33(6): 983-4.
    連結:
  6. Reinehr CPH, Bakos RM. Actinic keratoses: review of clinical, dermoscopic, and therapeutic aspects. An Bras Dermatol 2019; 94(6): 637-57.
    連結:
  7. Ishihara K, Saida T, Otsuka F, Yamazaki N. Statistical profiles of malignant melanoma and other skin cancers in Japan: 2007 update. Int J Clin Oncol 2008; 13(1): 33-41.
    連結:
  8. Lebwohl M. Actinic keratosis: epidemiology and progression to squamous cell carcinoma. Br J Dermatol 2003; 149(Suppl): 31-3.
    連結:
  9. Navarrete-Dechent C, Marghoob AA, Marchetti MA. Contemporary management of actinic keratosis. J Dermatolog Treat 2021; 32(5): 572-4.
    連結:
  10. Werner RN, Sammain A, Erdmann R, Hartmann V, Stockfleth E, Nast A. The natural history of actinic keratosis: a systematic review. Br J Dermatol 2013; 169(3): 502-18.
    連結:
  11. Agostinis P, Berg K, Cengel KA, et al. Photodynamic therapy of cancer: an update. CA Cancer J Clin 2011; 61(4): 250-81.
    連結: