補充孕烯醇酮對增強式運動後排球選手肌肉損傷的影響

The Effect of Pregnenolone Supplement on Muscle Damage after Plyometric Training for Volleyball Players

10.6127/JEPF.2008.07.06

陳浚良(Chun-Liang Chen)；吳茂盛(Mao-Sheng Wu)；黃奕仁(Yi-Jen Huang)；何建德(Chien-Te Ho)；蔡櫻蘭(Ying-Lan Tsai)；郭家驊(Chiao-Hua Kuo)

孕烯醇酮 ； 硫酸化脫氫異雄固酮鹽 ； 睪固酮 ； 肌酸激酶 ； 肌肉損傷 ； pregnenolone ； DHEA-S ； testosterone ； CK ； muscle damage

運動生理暨體能學報

7輯（2008 / 05 / 20）

61 - 69

繁體中文

Plyometric training, usually served as one drill to enhance bouncing ability of volleyball players, would cause more muscle damage. Pregnenolone was one precursor of sex steroid hormone. This study was to investigate the effect of oral pregnenolone after plyometric training on serum DHEA-S, testosterone, cholesterol, and muscle damage. Ten male professional volleyball players were randomized to the control and experimental groups. Following single plyometric training, the control group was given placebo intake and the experimental group was oral pregnenolone for one week during which fasting blood sample every morning was collected to analyze DHEA-S, testosterone, cholesterol and CK. After two weeks, two groups crossover with the same procedure. The results found that CK AUC was lower in the experimental group than the control group (the control group: 1097.23±308.92＞the experimental group: 346.78±175.06). However, no significant changes were noted in serum DHEA-S, testosterone and cholesterol. The result denoted that oral pregnenolone effectively reduced muscle damage from plyometric training with no effect on DHEA-S and testosterone, which suggested that pregnenolone is capable to diminish muscle damage from high-intensity training without controversial issues of illicit drug.

Plyometric training, usually served as one drill to enhance bouncing ability of volleyball players, would cause more muscle damage. Pregnenolone was one precursor of sex steroid hormone. This study was to investigate the effect of oral pregnenolone after plyometric training on serum DHEA-S, testosterone, cholesterol, and muscle damage. Ten male professional volleyball players were randomized to the control and experimental groups. Following single plyometric training, the control group was given placebo intake and the experimental group was oral pregnenolone for one week during which fasting blood sample every morning was collected to analyze DHEA-S, testosterone, cholesterol and CK. After two weeks, two groups crossover with the same procedure. The results found that CK AUC was lower in the experimental group than the control group (the control group: 1097.23±308.92＞the experimental group: 346.78±175.06). However, no significant changes were noted in serum DHEA-S, testosterone and cholesterol. The result denoted that oral pregnenolone effectively reduced muscle damage from plyometric training with no effect on DHEA-S and testosterone, which suggested that pregnenolone is capable to diminish muscle damage from high-intensity training without controversial issues of illicit drug.

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