停經婦女代謝症候群之研究

Metabolic Syndrome in Post-Menopausal Women

10.29462/TGG.200507.0004

林文元(Wen-Yuan Lin)；劉秋松(Chiu-Shong Liu)；林正介(Chen-Chieh Lin)；陳慶餘(Chin-Yu Chen)；李龍騰(Long-Teng Lee)；黃國晉(Kuo-Chin Huang)

代謝症候群 ； 停經 ； 肥胖 ； 胰島素阻抗 ； metabolic syndrome ； menopause ； obesity ； insulin resistance

台灣老年醫學雜誌

1卷1期（2005 / 07 / 01）

26 - 33

繁體中文

目標：本研究主要之目的乃探討停經婦女代謝症候群與年齡、肥胖及胰島素阻抗的關係。 方法：以1998年參加北台灣某醫學中心心血管疾病危險因子調查之停經婦女共237人（平均年齡53.2±4.6歲，年齡範圍43-70歲）為研究樣本，採用美國國家膽固醇教育計畫成人治療指引第三版(NCEP-ATPIII)及其修正版（腰圍大於80公分）的代謝症候群定義，分析其盛行率，並採用多重邏輯式回歸法分析代謝症候群及其相關因子之關係。 結果：以NCEP-ATPIII為代謝症候群標準來看，停經婦女之盛行率為9.7%，若採用修正版，其盛行率是13.9%，盛行率隨著年齡增加而增加；此外，以多重邏輯式回歸法分析經調整年齡變項後，身體質量指數(BMI)與胰島素阻抗是獨立相關於代謝症候群。 結論：停經後女性代謝症候群隨著年齡增加而增加，肥胖及胰島素阻抗可能在停經婦女的代謝症候群發展上扮演重要的角色。

Objectives: To investigate the prevalence of metabolic syndrome and its related factors among post-menopausal women. Methods: A total of 237 post-menopausal women (mean age: 53.2±4.6 years; range: 43-70 years) were recruited for a survey on the risk factors of cardiovascular disease (CVD) conducted by a medical center in North Taiwan in 1988. We used the U.S. National Cholesterol Education Program (NCEP) Adult Treatment Panel Ⅲ (ATPIII) definition of metabolic syndrome and its modified criteria (central obesity: waist circumference ＞80 cm). A multiple logistic regression analysis was adopted to explore the relationship between metabolic syndrome, age, body mass index (BMI), and insulin resistance (homeostasis model assessment-insulin resistance, HOMA-IR). Results: The prevalence of metabolic syndrome in post-menopausal women in these subjects read 9.7%, and the prevalence rose to 13.9% when the modified criteria were used. The prevalence of metabolic syndrome increased with age. In multiple logistic regression analysis with adjustment for age, both BMI and HOMA-IR were independently associated with the metabolic syndrome. Conclusions: The prevalence of metabolic syndrome was positively related to the increasing age in post-menopausal women. Both obesity and insulin resistance may play an important role in the development of metabolic syndrome among the post-menopausal women.