酒精性肝病的中醫療法

The Case Report on Chinese Medicine Treatment for Alcoholic Liver Disease

10.7102/JTCIM.201412_12(2).0001

鄭振鴻(Chen-Hung Cheng)

酒精性肝病 ； 乙醛 ； 黃疸 ； alcoholic liver disease ； alcohol ； Jaundice

中醫內科醫學雜誌

12卷2期（2014 / 12 / 01）

1 - 6

繁體中文

酒精性肝病（alcoholic liver disease，ALD）是由於長期大量的乙醇攝入導致的肝臟損害及其一系列病變，初期常表現為脂肪肝，進而進展為酒精性肝炎、酒精性肝纖維化和酒精性肝硬化。近年來工商業的發達，交際應酬使酒精消耗量逐年上升。適量飲酒對人類健康無明顯損害，但過量則嚴重威脅人類健康。肝臟是酒精代謝主要器官，在酒精（乙醇）代謝中，可以將乙醇轉化為乙醛，乙醛在肝內具有極強的化學活性和毒性作用，所產生的內毒素可誘導脂肪變性和肝細胞凋亡。西醫至今無特殊療法，唯一只有戒酒和戒酒綜合證的防治。中醫可以依辨證論治的病因分六種證型來治療因脂肪肝、肝炎、肝硬化、黃疸的症狀治療上有不同療效。希望未來中西醫的結合能夠提出一個重點研究。

Alcoholic liver disease(ALD) is due to taking in a large volume alcohol for a long time, resulting in the damage of liver. At the early stage of the disease, fatty liver happens, and then becomes alcoholic hepatitis, fibrosis of liver, and liver cirrhosis. Because of the development of industrialization, social activities make the consumption of alcohol raised. There is no obvious damage of human health if drinking adequately. However, drinking too much damages human health seriously. Liver is the organ that metabolizes alcohol. When metabolizing alcohol, alcohol is transformed into Acetaldehyde. Acetaldehyde possesses strong chemical activity and toxin, which would lead to death of liver cell. Until now, there is no special treatment in Western medication. The only way is to give up drinking and prevent alcohol withdrawal syndrome. Traditional Chinese Medical uses syndrome differentiation and treatment to treat fatty liver, alcoholic hepatitis, fibrosis of liver, liver cirrhosis, and Jaundice by six types of syndromes and the effectiveness is different. Hope the combination of Traditional Chinese Medication and Western Medication will focus on this research.

1. Canbay, A,Taimr, P,Torok, N(2003).Apoptotic body enqulfment by a human stellate cell line is Profibrogenic.Lab.Invest.,83,655-663.
2. Czrlock, AJ(2001).Undrstanding the pathogegesis of autoimmune hepatitis.The American Jou.of Gastroentrology,96(4),1224-1231.
3. Kaufman, RJ(1999).Stress singling from The lumen of the endoplasmic reticulum coordination of gene transcriptional and translation controls.Genes Dev,13,1211-1233.
4. Pooley(2013)。Sherlock 肝膽病學。北京人民衛生出版社。
5. Sass, DA(2001).Shaikhos.Alcoholic hepatitis Clinic Liver Disease,10(2),219-237.
6. 王泰玲、趙靜波(1997)。酒精性肝病的病理。胃腸病學和肝病學雜誌，6(1)，4-7。
7. 任萬華(2013)。肝病診斷與治療。人民軍出版社。
8. 向國卿、孟曉丹、王炳元(2009)。酒精與B 型肝炎病毒重疊的肝硬化的臨床預後探討。中華肝臟病雜誌，17(1)，72-73。
9. 曾民德、范建高(2010)。酒精性肝病診療指南。臨床肝膽病雜誌，26(3)，229-232。