题名

左旋肉鹼的補充對男子足球選手運動表現與生化值之影響

并列篇名

The Effect of L-Carnitine Supplementation on Male Soccer Players' Exercise Performance and Biochemical Parameter

DOI

10.6569/NTUJPE.201003_(17).0004

作者

張敏娣(Min-Ti Jhang);邱奕文(Yi-Wen Chiou);李寧遠(Ning-Yuean Lee)

关键词

左旋肉鹼 ; 運動表現 ; 生化值 ; L-carnitine ; exercise performance ; biochemical parameters

期刊名称

臺大體育學報

卷期/出版年月

17輯(2010 / 03 / 01)

页次

65 - 78

内容语文

繁體中文

中文摘要

Objective: L-carnitine is an ergogenic aid, which helps to transport free fatty acid into mitochondria in membrane of muscle cells, increases the metabolic rate of fatty acid, and leads to produce energy rapidly. Therefore, the aim of present study was to investigate the effect of L-carnitine supplementation on male soccer players' exercise performance and biochemical parameters after training. Methods: A double blind, random design was used. Male soccer players would be divided into L-carnitine or placebo group. Subjects received 3,200 mg L-carnitine or placebo orally per day for 3 weeks. The measurements included of exercise performance (twelve minutes run-walk test), and blood sampling of soccer players after training were analyzed for biochemical parameters, including of glucose, ammonia, lactic acid, free fatty acid, creatine kinase. Within-group variations for each variable were tested using Student's paired t test. Student's independent t test was used for differences detected among two groups. The level of significance was set at p<.05. Results: The results showed that exercise performance of L-carnitine group before supplement was significantly better than after supplement (p<.05), but caused no significant difference between two groups. The biochemical parameters after training showed that no significant difference was between L-carnitine group and placebo group in plasma glucose, ammonia, lactate, free fatty acid and serum creatine kinase. Conclusions: L-carnitine supplementation may not affecting exercise performance and other biochemical parameters of male soccer players.

英文摘要

Objective: L-carnitine is an ergogenic aid, which helps to transport free fatty acid into mitochondria in membrane of muscle cells, increases the metabolic rate of fatty acid, and leads to produce energy rapidly. Therefore, the aim of present study was to investigate the effect of L-carnitine supplementation on male soccer players' exercise performance and biochemical parameters after training. Methods: A double blind, random design was used. Male soccer players would be divided into L-carnitine or placebo group. Subjects received 3,200 mg L-carnitine or placebo orally per day for 3 weeks. The measurements included of exercise performance (twelve minutes run-walk test), and blood sampling of soccer players after training were analyzed for biochemical parameters, including of glucose, ammonia, lactic acid, free fatty acid, creatine kinase. Within-group variations for each variable were tested using Student's paired t test. Student's independent t test was used for differences detected among two groups. The level of significance was set at p<.05. Results: The results showed that exercise performance of L-carnitine group before supplement was significantly better than after supplement (p<.05), but caused no significant difference between two groups. The biochemical parameters after training showed that no significant difference was between L-carnitine group and placebo group in plasma glucose, ammonia, lactate, free fatty acid and serum creatine kinase. Conclusions: L-carnitine supplementation may not affecting exercise performance and other biochemical parameters of male soccer players.

主题分类 社會科學 > 體育學
参考文献
  1. Arenas, J.,Huertas, R.,Campos, Y.,Diaz, A. E.,Villalon, J. M.,Vilas, E.(1994).Effects of L-carnitine on the pyruvate dehydrogenase complex and carnitine palmitoyl transferase activities in muscle of endurance athletes.FEBS Letters,341(1),91-93.
  2. Arenas, J.,Ricoy, J. R.,Encinas, A. R.,Pola, P.,D''Iddio, S.,Zeviani, M.(1991).Carnitine in muscle, serum, and urine of nonprofessional athletes: Effects of physical exercise, training, and L-carnitine administration.Muscle & Nerve,14(7),598-604.
  3. Barnett, C.,Costill, D. L.,Vukovich, M. D.,Cole, K. J.,Goodpaster, B. H.,Trappe, S. W.(1994).Effect of L-carnitine supplementation on muscle and blood carnitine content and lactate accumulation during high-intensity sprint cycling.International Journal of Sport Nutrition,4(3),280-288.
  4. Brass, E. P.(2000).Supplemental carnitine and exercise.The American Journal of Clinical Nutrition,72(2 Suppl),618S-623S.
  5. Broad, E. M.,Maughan, R. J.,Galloway, S. D.(2005).Effects of four weeks L-carnitine Ltartrate ingestion on substrate utilization during prolonged exercise.International Journal of Sport Nutrition and Exercise Metabolism,15(6),665-679.
  6. Broad, E. M.,Maughan, R. J.,Galloway, S. D.(2008).Carbohydrate, protein, and fat metabolism during exercise after oral carnitine supplementation in humans.International Journal of Sport Nutrition and Exercise Metabolism,18(6),567-584.
  7. Colombani, P.,Wenk, C.,Kunz, I.,Krahenbuhl, S.,Kuhnt, M.,Arnold, M.(1996).Effects of L-carnitine supplementation on physical performance and energy metabolism of endurance-trained athletes: A double-blind crossover field study.European Journal of Applied Physiology and Occupational Physiology,73(5),434-439.
  8. Dragan, G. I.,Vasiliu, A.,Georgescu, E.,Dumas, I.(1987).Studies concerning chronic and acute effects of L-carnitine on some biological parameters in elite athletes.Physiologie,24(1),23-28.
  9. Fox, E. L.,Bowers, R. W.,Foss, M. L.(1993).The Physiological Basis for Exercise and Sport (5th ed.).Madison, Wis.:Brown & Benchmark Publishers.
  10. Giamberardino, M. A.,Dragani, L.,Valente, R.,Di Lisa, F.,Saggini, R.,Vecchiet, L.(1996).Effects of prolonged L-carnitine administration on delayed muscle pain and CK release after eccentric effort.International Journal of Sports Medicine,17(5),320-324.
  11. Gorostiaga, E. M.,Maurer, C. A.,Eclache, J. P.(1989).Decrease in respiratory quotient during exercise following L-carnitine supplementation.International Journal of Sports Medicine,10(3),169-174.
  12. Hargreaves, A.,Bate, R.(2010).Skills & Strategies for Coaching Soccer (2nd ed.).Champaign, IL:Human Kinetics.
  13. Janssen, G. M.,Scholte, H. R.,Vaandrager-Verduin, M. H.,Ross, J. D.(1989).Muscle carnitine level in endurance training and running a marathon.International Journal of Sports Medicine,10(Suppl 3),S153-155.
  14. Marconi, C.,Sassi, G.,Carpinelli, A.,Cerretelli, P.(1985).Effects of L-carnitine loading on the aerobic and anaerobic performance of endurance athletes.European Journal of Applied Physiology and Occupational Physiology,54(2),131-135.
  15. Muller, D. M.,Seim, H.,Kiess, W.,Loster, H.,Richter, T.(2002).Effects of oral L-carnitine supplementation on in vivo long-chain fatty acid oxidation in healthy adults.Metabolism: Clinical and Experimental,51(11),1389-1391.
  16. Panjwani, U.,Thakur, L.,Anand, J. P.,Singh, S. N.,Amitabh, Singh, S. B.(2007).Effect of L-carnitine supplementation on endurance exercise in normobaric/normoxic and hypobaric/hypoxic conditions.Wilderness & Environmental Medicine,18(3),169-176.
  17. Raven, P. B.,Gettman, L.R.,Pollock, M. L.,Cooper, K. H.(1976).A physiological evaluation of professional soccer players.British journal of sports medicine,10(4),209-216.
  18. Spiering, B. A.,Kraemer, W. J.,Vingren, J. L.,Hatfield, D. L.,Fragala, M. S.,Ho, J. Y.(2007).Responses of criterion variables to different supplemental doses of L-carnitine Ltartrate.Journal of Strength and Conditioning Research/National Strength & Conditioning Association,21(1),259-264.
  19. Stephens, F. B.,Constantin-Teodosiu, D.,Laithwaite, D.,Simpson, E. J.,Greenhaff, P. L.(2006).An acute increase in skeletal muscle carnitine content alters fuel metabolism in resting human skeletal muscle.The Journal of Clinical Endocrinology and Metabolism,91(12),5013-5018.
  20. Trappe, S. W.,Costill, D. L.,Goodpaster, B.,Vukovich, M. D.,Fink, W. J.(1994).The effects of L-carnitine supplementation on performance during interval swimming.International Journal of Sports Medicine,15(4),181-185.
  21. Vecchiet, L.,Di Lisa, F.,Pieralisi, G.,Ripari, P.,Menabo, R.,Giamberardino, M. A.(1990).Influence of L-carnitine administration on maximal physical exercise.European Journal of Applied Physiology and Occupational Physiology,61(5-6),486-490.
  22. Volek, J. S.,Kraemer, W. J.,Rubin, M. R.,Gomez, A. L.,Ratamess, N. A.,Gaynor, P.(2002).L-Carnitine L-tartrate supplementation favorably affects markers of recovery from exercise stress.American Journal of Physiology. Endocrinology and Metabolism,282(2),E474-482.
  23. Wachter, S.,Vogt, M.,Kreis, R.,Boesch, C.,Bigler, P.,Hoppeler, H.(2002).Longterm administration of L-carnitine to humans: Effect on skeletal muscle carnitine content and physical performance.Clinica Chimica Acta; International Journal of Clinical Chemistry,318(1-2),51-61.
  24. 李寧遠、巫錦霖、郭婕、陳文詮、張志平、程一雄、詹貴惠、蔡櫻蘭、鍾珮(2005)。運動營養學。臺北市:華香園。
  25. 林正常、林貴福、徐台閣、吳慧君譯(2005)。運動生理學。臺北市:藝軒圖書。
  26. 陳鞠伎(2005)。桃園縣,國立體育學院教練研究所。