题名

頭頸癌病人接受放射線治療後生活品質之相關因素

并列篇名

The factors affecting the post-radiotherapy quality of life of patients suffering head and neck cancer

作者

許瓊惠(Chiung-Hui Hsu);李慧琦(Hui-Chi Li);洪瑩朱(Ying-Chu Hung)

关键词

頭頸癌 ; 放射治療 ; 生活品質 ; head and neck cancer ; radiotherapy ; quality of life

期刊名称

台灣健康照顧研究學刊

卷期/出版年月

24期(2021 / 07 / 01)

页次

1 - 15

内容语文

繁體中文

中文摘要

台灣的頭頸癌死亡率很高,但鮮少研究探討這些病人接受放療後生活品質之相關因素。本研究目的主要是探討頭頸癌病人接受放射治療後的生活品質之相關因素。為觀察性研究,採方便取樣。評估工具為包括:生活品質評估量表為簡明版世界衛生組織生活品質問卷及歐洲生活品質量表,功能狀態為柯氏量表。共58位收案。研究結果發現治療後生活品質的生理健康範疇與治療前生理健康範疇呈顯著性相關。心理範疇顯著性相關因子為家庭收入狀況。社會關係範疇的顯著性相關因子為功能狀態,環境範疇顯著性相關因子為治療前環境範疇及家庭收入狀況。而工作狀態與歐洲生活品質量表達顯著性相關。建議改善病人治療前身體健康狀況及功能狀態,並運用社會資源以增加頭頸癌病人放射治療後的生活品質。

英文摘要

Although head and neck (H&N) cancer has a high mortality rate in Taiwan, less is known about the effects of radiotherapy treatment on patients' QOL and the factors that may contribute to these changes. The study aims to investigate the factors of quality of life (QOL) for H&N cancer patients after radiotherapy. An observational longitudinal study was used to analyse the QOL of patients. The World Health Organization Quality of Life Assessment (WHOQOL-BREF) and Euro QOL five-dimensional questionnaire (EQ-5D) were used to assess QOL. Performance status was measured by the Karnofsky Performance Scale (KPS) Index. 58 cases were included in the study. Physical health prior to radiotherapy had a significant correlation with physical health post-radiotherapy, whereas psychological health correlated significantly with family income. Social factors were significantly correlated to the KPS index. Employment status significantly correlated to ED-5D. It is recommended to improve the patient's physical health and functional status before treatment, and to use social resources to increase the quality of life of patients with head and neck cancer after radiotherapy.

主题分类 醫藥衛生 > 預防保健與衛生學
醫藥衛生 > 社會醫學
参考文献
  1. Aggarwal, V. P.,Lakshminarayan Rao, D. C.,Mathur, A.,Batra, M.,Makkar, D. K.(2015).Prevalence of head and neck and oral cancer in Rajasthan: An infirmary based retrospective study.Clinical Cancer Investigation Journal,4(3),339-343.
  2. Bilal, S.,Doss, J. G.,Cella, D.,Rogers, S. N.(2015).Quality of life associated factors in head and neck cancer patients in a developing country using the FACT-H&N.Journal of Cranio-Maxillofacial Surgery,43(2),274-280.
  3. Brooks, R.,Rabin, R.,de Charro, F.(2003).The Measurement and Valuation of Health Status Using EQ-5D: A European Perspective.The Netherlands:Kluwer.
  4. Caniçali Primo, C.,Dias Cesar, F.,de Fátima Almeida Lima, E.,Caniçali, R. A.,Marabotti Costa Leite, F.(2016).Nursing care to patients with head and neck cancer undergoing radiotherapy.Revista de Pesquisa: Cuidado e Fundamental,8(1),3820-3831.
  5. Chen, S. C.,Liao, C. T.,Chang, J. T.(2011).Orofacial pain and predictors in oral squamous cell carcinoma patients receiving treatment.Oral Oncology,47(2),131-135.
  6. Citak, E.,Tulek, Z.(2013).Longitudinal quality of life in Turkish patients with head and neck cancer undergoing radiotherapy.Supportive Care in Cancer,21(8),2171-2183.
  7. Giuliani, M.,Papadakos, J.,Broadhurst, M.,Jones, J.,McQuestion, M.,Le, L. W.,Beck, L.,Waldron, J.,Ringash, J.(2019).The prevalence and determinants of return to work in head and neck cancer survivors.Supportive Care in Cancer: Official Journal of The Multinational Association Of Supportive Care in Cancer,27(2),539-546.
  8. Hawro, T.,Zalewska, A.,Hawro, M.,Kaszuba, A.,Królikowska, M.,Maurer, M.(2015).Impact of psoriasis severity on family income and quality of life.Journal of The European Academy of Dermatology and Venereology,29(3),438-443.
  9. Karnofsky, D. A., Abelmann, W. H., Craver, L. F., & Burchenal, J. H. (1948). The use of the nitrogen mustards in the palliative treatment of carcinoma. With particular reference to bronchogenic carcinoma. Cancer, 1(4), 634-656. http://doi:<634::aid-cncr2820010410>3.0.co;2-l
  10. Kaufmann, A.,Schmidt, H.,Ostheimer, C.,Ullrich, J.,Landenberger, M.,Vordermark, D.(2015).Quality of life in very elderly radiotherapy patients: a prospective pilot study using the EORTC QLQ-ELD14 module.Supportive Care in Cancer,23(7),1883-1892.
  11. Lee, J. A.,Kim, S. Y.,Kim, Y.,Oh, J.,Kim, H. J.,Jo, D. Y.,Kwon, T., G.,Park, J. H.(2014).Comparison of health-related quality of life between cancer survivors treated in designated cancer centers and the general public in Korea.Japanese Journal of Clinical Oncology,44(2),141-152.
  12. Liao, L.J.,Hsu, W.L.,Lo, W.C.,Cheng, P.W.,Shueng, P.W.,Hsieh, C.H.(2019).Health-related quality of life and utility in head and neck cancer survivors.BMC Cancer,19(1),1-10.
  13. Liu, H.-E.(2008).Changes of satisfaction with appearance and working status for head and neck tumour patients.Journal of Clinical Nursing,17(14),1930-1938.
  14. Massa, S. T.,Rohde, R. L.,McKinstry, C.,Gresham, M.,Osazuwa-Peters, N.,Ward, G. M.,Walker, R. J.(2018).An assessment of patient burdens from head and neck cancer survivorship care.Oral Oncology,82,115-121.
  15. McQuestion, M.(2011).Evidence-based skin care management in radiation therapy: clinical update.Seminars in Oncology Nursing,27(2),e1-e17.
  16. McQuestion, M.,Fitch, M.,Howell, D.(2011).The changed meaning of food: Physical, social and emotional loss for patients having received radiation treatment for head and neck cancer.European Journal of Oncology Nursing: The Official Journal of European Oncology Nursing Society,15(2),145-151.
  17. Mercadante, S.,Aielli, F.,Adile, C.,Ferrera, P.,Valle, A.,Fusco, F.,Cartoni, C.,Massimo, P.,Masedu, F.,Valenti, M.,Porzio, G.(2015).Prevalence of oral mucositis, dry mouth, and dysphagia in advanced cancer patients.Supportive Care in Cancer,23(11),3249-3255.
  18. Movsas, B.,Scott, C.,Watkins-Bruner, D.(2006).Pretreatment factors significantly influence quality of life in cancer patients: a Radiation Therapy Oncology Group (RTOG) analysis.International Journal of Radiation Oncology, Biology, Physics,65(3),830-835.
  19. Rogers, S. N.,Harvey-Woodworth, C. N.,Hare, J.,Leong, P.,Lowe, D.(2012).Patients' perception of the financial impact of head and neck cancer and the relationship to health-related quality of life.The British Journal of Oral & Maxillofacial Surgery,50(5),410-416.
  20. Sehlen, S.,Hollenhorst, H.,Lenk, M.,Schymura, B.,Herschbach, P.,Aydemir, U.,Dühmke, E.(2002).ATL>Only sociodemographic variables predict quality of life after radiography in patients with head-and-neck cancer.International Journal of Radiation Oncology, Biology, Physics,52(3),779.
  21. So, W.,Choi, K.,Chen, J.,Chan, C.,Chair, S.,Fung, O.,Wan, R.,Mak, S.,Lin, W.,Ng, W.,Yu, B.(2014).Quality of life in head and neck cancer survivors at 1 year after treatment: the mediating role of unmet supportive care needs.Supportive Care in Cancer,22(11),2917-2926.
  22. Vaz, A.,Conde, D.,Costa-Paiva, L.,Morais, S.,Esteves, S.,Pinto-Neto, A.(2011).Quality of life and adverse events after radiotherapy in gynecologic cancer survivors: a cohort study.Archives of Gynecology and Obstetrics,284(6),1523-1531.
  23. Visacri, M. B.,Ferrari, G.B.,Pimentel, R.,Ambrósio, R. D. F. L.,Lima, C. S. P.,Mazzola, P. G.,Moriel, P.(2015).Evaluation of the quality of life of patients before treatment of squamous cell carcinoma of the head and neck by means of chemoradiotherapy.Contemporary Oncology / Wspolczesna Onkologia,19(2),148-153.
  24. World Health Organization. (2019). WHOQOL: Measuring Quality of Life. Retrieved from https://www.who.int/healthinfo/survey/whoqol-qualityoflife/en/
  25. Yeh, S. A.(2010).Radiotherapy for Head and Neck Cancer.Seminars in Plastic Surgery,24(2),127-136.
  26. Żmijewska-Tomczak, M.,Milecki, P.,Olek-Hrab, K.,Hojan, K.,Golusiński, W.,Rucińska, A.,Adamska, A.(2014).Factors influencing quality of life in patients during radiotherapy for head and neck cancer.Archives of Medical Science,10(6),1153-1159.
  27. 台灣版世界衛生組織生活品質問卷發展小組(2000)。台灣版世界衛生組織生活品質問卷之發展簡介。中華公共衛生雜誌,4(19),315-324。
  28. 姚開屏(2002)。台灣版世界衛生組織生活品質問卷之發展與應用。台灣醫學,2(6),193-200。
  29. 范綱行,林倩伃,張東杰(2015)。口腔癌的放射治療。台灣癌症醫學雜誌,2(2),117-126。
  30. 許麗珠(2006)。放射線治療的發展與臨床應用之專題報導。腫瘤護理雜誌,2(6),65-73。
  31. 衛生福利部 (2019)。《108 年度死因統計》。衛生福利部網頁(https://dep.mohw.gov.tw/DOS/lp-4927-113.html)