The Effect of Aqueous Methanolic Stem Bark Extracts of Acacia Polyacantha on Sexual Behaviour, Serum Testosterone Levels in Male Wistar Rats

A.U. Wawata；A.A.U. Dikko；K.V. Olorunshola；M.U. Wawata；A. Attahir；M.K. Ahmed

Fertility ； infertility ； sexual behavior ； sperm counts

Asian Journal of Medical Sciences

2卷3期（2010 / 06 / 25）

138 - 140

英文

The aim of the research is to determine the possible application of Acacia polycantha in the treatment of sexual behavior and serum testosterone. We determined the LD_50 from the dried bark of the plant to be 3808.88 kg/body weight, then treated the wistar rats with 150, 300 and 600mg/kg body weight that was shown to have effects on mounting behavior which increased from 6.20±2.49 in control to up to 8.40±3.25 with concentration of 150mg/kg and falls to 3.80±1.35 and 0.20+0.20 with 300 and 600mg/kg body weight respectively. On the other hand the testosterone levels increased from 3.62±2.19 in control to 6.88±1.78 with 150mb/kg and 7.18±2.38 and 7.78±2.38 with 300 and 600mg/kg respectively while falling insignificantly below the control to 3.60±1.34 with Viagra 150mg/kg. We concluded therefore based on the experiment conducted that Acacacia polycantha plant could be used to enhance sexual behavior after further screening of its active ingredients.