Prevalence of STI Pathogens in HIV-Infected and Non-Infected Women: Implications for Acquisition and Transmission of Hiv in Nigeria

I.O. Oyewole；G.N. Anyasor；E.C. Michael-Chikezie

Bacterial vaginosis ； Candida albicans ； HIV ； infected and non-infected ； pus cells ； Trichomonas vaginalis

Asian Journal of Medical Sciences

2卷3期（2010 / 06 / 25）

163 - 166

英文

The prevalence of STI pathogens in HIV-infected and non infected women attending HIV and STI clinic of the Olabisi Onabanjo University Teaching Hospital (OOUTH), Sagamu, Ogun state, Nigeria was compared for possible implications in the acquisition and transmission of HIV. The study involved the collection of urine and vagina swabs using sterile universal bottles and Evapon swab sticks respectively from 100 females of which 34 were HIV-positive and 66 HIV-negative. The samples were screened at the Babcock University Microbiology Laboratory for the presence of Trichomonas vaginalis, Candida albicans, pus cells and bacterial vaginosis. Twelve percent of HIV-positive patients were infected with T. vaginalis, 77% with C. albicans, 68% with bacterial vaginosis and 35% with pus cells (indicates the presence of cervical infections). Only 2% of the HIV-negative patients were infected with T. vaginalis 20% with C. albicans, 40% with bacterial vaginosis and 5% with pus cells. The statistical analysis showed a significant difference in the infection rates between HIV infected and non- infected patients (p＜0.05). Since STIs are not only associated with their own morbidity, but also facilitate sexual transmission and infectivity of HIV, there is therefore the need for aggressive prevention, testing and treatment of ST Is in order to reduce acquisition and transmission of HIV.