新型微流體晶片與實驗系統的研製

Research and Fabrication of New Microfluidic Chips and Experimental System

10.6989/JN.200612.0053

廖威量(Wei-Lianq Liaw)；何克威(Ker-Way Ho)；邱俊文(Jun-Wen Chiou)；呂江霖(Chiang-Lin Lu)

旋轉座標 ； 微流體晶片 ； 平面驅動 ； rotating coordinates ； microfluidic chips ； plane driving

南亞學報

26期（2006 / 12 / 01）

53 - 66

繁體中文

本研究以「旋轉座標」的原理，搭配小型無線攝影機的應用，研製出可隨旋轉平台旋轉，且能同步「靜止」拍攝平台上微流體晶片受離心力影響變化的觀測裝置－「閃碟3號」，與之前本研究群以「定頻器」原理發展的類似機台「閃碟2號」比較，此實驗系統具有較簡單、經濟、易攜帶與無觀測時差等優點。本研究亦以實驗驗證發展出離心式「非徑向」微流體驅動的概念與理論，提出新型「平面驅動」式生物晶片的模型，為離心式微流體晶片的多樣性與可能應用，開啟了一個新的發展與設計方向。

Based on concept of ”rotating coordinates”, this study used small wireless camera to build a rotary platform and an observation device that can capture still shoots of the changes of the microfluidic chips under centrifugal force synchronously-”Flash 3”. Compared with Flash 2, which was developed based on the concept of ”Stroboscope” by our team, Flash 3 experimental system has advantages of simple design, economical cost, portability and all-time observation. This study proposed concepts and theories concerning centrifugal ”non-radial” microfluidic drive based on experimental verification, and developed the new ”plane driving” biochips to provide diversity and applicability, as well as a new direction of development and design.