题名

玫瑰茄（洛神花；Hibiscus sabdariffa）在健康管理之應用

并列篇名

Hibiscus sabdariffa in health management application

DOI

10.6285/MIC.201808_7(S2).0018

作者

林文宏(Wun-Hong Lin)；朱基銘(Chi-Ming Chu)；陳俊合(Chun-He Chen)；盧俊吉(Chun-Chi Lu)

关键词

玫瑰茄 ； 花青素 ； 原兒茶酸 ； 抗發炎 ； Hibiscus sabdariffa ； anthocyanins ； prorocatechuic acid ； anti-inflammatory

期刊名称

管理資訊計算

卷期/出版年月

7卷特刊2（2018 / 08 / 01）

页次

173 - 187

内容语文

繁體中文
中文摘要

在本文綜述中說明玫瑰茄 (洛神花；Hibiscus sabdariffa, HS) 萃取物應用於人類相關疾病，除對其生物活性、緩解作用等研究做一整理，也對此傳統藥用植物的生化、藥理學的隨機臨床試驗 (randomized clinical trial; RCT)，並一併提供安全性和毒性的研究整理。這一綜合的證據說明，HS 萃取物有可能作為多種人類疾病的有效緩解物。本研究係檢視HS 萃取物對發炎反應的可能影響，藉由能否抑制包括一氧化氮(nitric oxide, NO)、介白素6 (cytokine interleukin 6; IL-6)、腫瘤壞死因子-α (tumornecrosis factor; TNF-α) 三種發炎的生成。結果顯示，HS 萃取物能抑制細菌脂多醣(Lipopolysaccharide; LPS) 所刺激的發炎IL-6 反應；同時，HS 萃取物對受測細胞並無細胞毒性。因此，本研究結果，仍需通過臨床實驗驗證，以及更多數量的動物和人類案例研究，為提供公共健康益處之有效建議。
英文摘要

In this comprehensive narrative literature review indicated that Hibiscus sabdariffa Flower Extract (HS) can effectively alleviate human-related diseases. The reviews also provided safety and toxicological information on this traditional medical through pharmacological randomized clinical trial (RCT) of phytochemistry and biochemistry. The comprehensive reviews also showed that HS extracts may serve as a relief for human disease. The objective of this study was to determine the effects of HS extract on lipopolysaccharide (LPS)-stimulated inflammation by suppressing three pro-inflammatory mediators, including nitric oxide (NO), cytokine interleukin 6 (IL-6) as well as tumor necrosis factor-α (TNF-α). The results showed that the HS extract exerted anti-inflammatory effect by suppressing inflammation, while cytotoxicity was not detected in the cells tested. Furthermore, the extract still needs to be verified by actual therapeutic practice and more high-quality animal and human studies to understand the effects of clinical trials. In practice, the purpose of the study hopes to enhance a wide range of public health benefits and well-being of humanity.
主题分类 基礎與應用科學 > 資訊科學
社會科學 > 管理學
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被引用次数
  1. 林文宏(2021)。植物提取物複方之面膜精華液其抗發炎之研究。美容科技學刊，18(1)，103-122。
  2. 葉耀南,林文宏,小泉清伊(2021)。探討花青素粉末複方抗發炎之研究。中醫本草健康促進期刊，5(1)，5-21。
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