题名

胸腔病例(三三五)前縱膈腔生殖細胞瘤

DOI

10.6666/ClinMed.2017.79.4.044

作者

林佑容;黃煦晴;張牧新;邱昭華

关键词

生殖細胞瘤(germ cell tumor) ; 前縱膈腔腫瘤(mediastinal tumor) ; 前縱膈腔(mediastinum)

期刊名称

臨床醫學月刊

卷期/出版年月

79卷4期(2017 / 04 / 28)

页次

240 - 245

内容语文

繁體中文

中文摘要

前縱膈腔是最常見的生殖腺外生殖細胞瘤(extragonodal germ cell tumor, EGCTs) 原發部位。臨床症狀可能有胸悶、咳嗽、喘、阻塞性肺炎、體重減輕、上腔靜脈症候群、發燒、噁心等。依據細胞型態及分泌之腫瘤指標又可分為精原性(seminomataous, germinomatous)和非精原性(non-seminomatous ) 。治療依據腫瘤分型有所不同,以手術切除及化學治療為主,輔以放射治療、血液幹細胞移植等。本病例為一位37歲男性,經確診前縱膈腔精原細胞瘤後,接受化學治療及局部放射治療。

主题分类 醫藥衛生 > 基礎醫學
醫藥衛生 > 社會醫學
参考文献
  1. (1997).International Germ Cell Consensus Classification: a prognostic factor-based staging system for metastatic germ cell cancers. International Germ Cell Cancer Collaborative Group.J. Clin. Oncol,15,594-603.
  2. Agarwala, AK,Perkins, SM,Abonour, R(2011).Salvage chemotherapy with highdose carboplatin and etoposide with peripheral blood stem cell transplant in patients with relapsed pure seminoma.Am J Clin Oncol,34,286-288.
  3. Albany, C,Einhorn, LH(2013).Extragonadal germ cell tumors: clinical presentation and management.Curr Opin Oncol,25,261-265.
  4. Bokemeyer, C,Nichols, CR,Droz, JP(2002).Extragonadal germ cell tumors of the mediastinum and retroperitoneum: results from an international analysis.J Clin Oncol,20,1864-1873.
  5. Einhorn, LH,Williams, SD,Chamness, A(2007).High-Dose Chemotherapy and Stem-Cell Rescue for Metastatic Germ-Cell Tumors.N Engl J Med,357,340-348.
  6. Gilligan, TD,Seidenfeld, J,Basch, EM(2010).American Society of Clinical Oncology Clinical Practice Guideline on uses of serum tumor markers in adult males with germ cell tumors.J Clin Oncol,28,3388-3404.
  7. Motzer, R,Bosl, G,Heelan, R(1987).Residual mass: an indication for further therapy in patients with advanced seminoma following systemic chemotherapy.J Clin Oncol,5,1064-1070.
  8. Ranganath, P,Kesler, KA,Einhorn, LH(2016).Perioperative Morbidity and Mortality Associated With Bleomycin in Primary Mediastinal Nonseminomatous GermCell Tumor.J Clin Oncol,34,4445-4447.
  9. Rusner, C,Trabert, B,Katalinic, A(2013).Incidence patterns and trends of gonadal and extragonadal germ cell tumors in Germany, 1998-2008.Cancer Epidemiol,37,370-373.
  10. Samuels, ML,Johnson, DE,Holoye, PY(1976).Large-dose bleomycin therapy and pulmonary toxicity. A possible role of prior radiotherapy.JAMA,235,1117-1120.
  11. Takeda, S,Miyoshi, S,Ohta, M(2003).Primary germ cell tumors in the mediastinum: a 50-year experience at a single Japanese institution.Cancer,97,367-376.
被引用次数
  1. 楊淑慧,王偉靜(2023)。一位縱膈腔卵黃囊瘤末期青年之護理經驗。志為護理-慈濟護理雜誌,22(2),87-95。