肉瘤肺轉移之外科觀點

10.6666/ClinMed.201804_81(4).0036

徐博奎

肺轉移(lung metastasis) ； 肉瘤(sarcoma) ； 手術(surgery)

臨床醫學月刊

81卷4期（2018 / 04 / 27）

210 - 213

繁體中文

肉瘤肺轉移的治療需要多專科團隊合作，外科手術切除在治療骨肉瘤肺轉移上具一定角色，手術適應症包括(1)原發部位已有效控制；(2)肺轉移可被完整切除；(3)病人狀況允許手術；及(4)沒有其他胸腔外轉移。微創胸腔鏡手術的進步對手術方面的觀念有很大影響。手術後的預後因子包括：組織型態、無病期間、是否有肺外病灶、對化學治療的反應、病灶數目、及是否能完整切除。

1. Billingsley, KG,Burt, ME,Jara, E(1999).Pulmonary metastases from soft tissue sarcoma: analysis of patterns of diseases and postmetastasis survival.Ann Surg,229,602-610.
2. Casson, AG,Putnam, JB,Natarajan, G(1992).Five-year survival after pulmonary metastasectomy for adult soft tissue sarcoma.Cancer,69,662-668.
3. Gadd, MA,Casper, ES,Woodruff, JM(1993).Development and treatment of pulmonary metastases in adult patients with extremity soft tissue sarcoma.Ann Surg,218,705-712.
4. Gossot, D,Radu, C,Girard, P(2009).Resection of pulmonary metastases from sarcoma: can some patients beneft from a less invasive approach?.Ann Thorac Surg,87,238-243.
5. Greenwood, A,West, D.(2013).Is a thoracotomy rather than thoracoscopic resection associated with improved survival after pulmonary metastasectomy?.Interact Cardiovasc Thorac Surg,17,720-724.
6. Guerrini, GP,Lo Faso, F,Vagliasindi, A(2017).The role of minimally invasive surgery in the treatment of lung metastases.J Invest Surg,30,110-115.
7. Kang, S,Kim, HS,Kim, S(2014).Post-metastasis survival in extremity soft tissue sarcoma: a recursive partitioning analysis of prognostic factors.Eur J Cancer,50,1649-1656.
8. Marulli, G,Mammana, M,Comacchio, G,Rea, F(2017).Survival and prognostic factors following pulmonary metastasectomy for sarcoma.J Thorac Dis,9,S1305-S1315.
9. Pfannschmidt, J,Klode, J,Muley, T(2006).Pulmonary metastasectomy in patients with soft tissue sarcomas: experiences in 50 patients.Thorac Cardiovasc Surg,54,489-492.
10. Stephens, EH,Blackmon, SH,Correa, AM(2011).Progression after chemotherapy is a novel predictor of poor outcomes after pulmonary metastasectomy in sarcoma patients.J Am Coll Surg,212,821-826.
11. Suzuki, M,Iwata, T,Ando, S(2006).Predictors of long-term survival with pulmonary metastasectomy for osteosarcomas and soft tissue sarcomas.J Cardiovasc Surg,47,603-608.
12. Treasure, T,Fiorentino, F,Scarci, M(2012).Pulmonary metastasectomy for sarcoma: a systematic review of reported outcomes in the context of Thames Cancer Registry data.BMJ Open,2,e001736.
13. Ueda, T,Uchida, A,Kodama, K(1993).Aggressive pulmonary metastasectomy for soft tissue sarcomas.Cancer,72,1919-1925.
14. Welter, S,Grabellus, F,Bauer, S(2012).Growth patterns of lung metastases from sarcoma: prognostic and surgical implications from histology.Interact Cardiovasc Thorac Surg,15,612-617.
15. Welter, S,Grabellus, F,Bauer, S(2011).Growth patterns of lung metastases from sarcomas.Virchows Arch,459,213-219.

1. 蘇俞萍,黃莉娟(2021)。一位骨肉瘤復發病人面臨安寧抉擇之護理經驗。榮總護理，38(1)，78-85。