题名

胃食道逆流診療新利器無線食道酸鹼檢測膠囊及熱射頻胃賁門緊縮術

DOI

10.6666/ClinMed.201901_83(1).0010

作者

吳文傑

关键词

胃食道逆流(gastroesophageal reflux) ; 內視鏡治療(endoscopic treatment) ; 熱射頻胃賁門緊縮術(Stretta procedure) ; 無線食道酸鹼檢測膠囊(Bravo capsule)

期刊名称

臨床醫學月刊

卷期/出版年月

83卷1期(2019 / 01 / 25)

页次

49 - 56

内容语文

繁體中文

中文摘要

國內約有四分之一的民眾受胃食道逆流困擾,醫師除了給予良好的生活飲食衛教以外,降低胃酸分泌的藥物治療為國內主要治療,氫離子幫浦阻斷劑更是解決了大部分病患不適的症狀。然而過去在胃食道逆流治療上國內仍有四個臨床困境,包括長期用藥的安全及經濟考量、難治型胃食道逆流診治、食道酸鹼檢測及機能檢查的不普及和病患接受外科手術治療意願低。如果治療不佳也可能會有長期併發症包括食道狹窄以及巴瑞特食道病變、食道腺癌等等,更重要的是患者的生活品質以及工作低落增加身心疾病的風險。國外也相當重視胃食道逆流的診治議題,尤其是在精確的診斷以及個人化的治療上,當中包括了無線食道酸鹼膠囊(Bravo capsule)、食道阻抗性的測量以及內視鏡的微創治療等都是近十年來的重點,今年也特別發表了胃食道逆流診斷的里昂專家共識,提供醫師臨床很好的指引。國內自去年開始引進了無線食道酸鹼檢測膠囊以及熱射頻胃賁門緊縮術(Stretta procedure)兩項新利器,筆者所在的醫院也都開始提供相關診治服務。本文將簡介無線食道酸鹼檢測膠囊以及熱射頻胃賁門緊縮術的應用與療效。

主题分类 醫藥衛生 > 基礎醫學
醫藥衛生 > 社會醫學
参考文献
  1. Dughera, L,Rotondano, G,De Cento, M(2014).Durability of Stretta Radiofrequency Treatment for GERD: Results of an 8-Year Follow-Up.Gastroenterol Res Pract,2014,1-5.
  2. Fass, R,Cahn, F,Scotti, DJ(2017).Systematic review and meta-analysis of controlled and prospective cohort efficacy studies of endoscopic radiofrequency for treatment of gastroesophageal reflux disease.Surg Endosc,31,4865-4882.
  3. Gyawali, CP,Kahrilas, PJ,Savarino, E(2018).Modern diagnosis of GERD: the Lyon Consensus.Gut,67,1351-1362.
  4. Khidir, N,Angrisani, L,Al-Qahtani, J(2018).Initial Experience of Endoscopic Radiofrequency Waves Delivery to the Lower Esophageal Sphincter (Stretta Procedure) on Symptomatic Gastroesophageal Reflux Disease Post-Sleeve Gastrectomy.Obes Surg,28,3125-3130.
  5. Liang, WT,Wu, JM,Wang, F(2014).Stretta radiofrequency for gastroesophageal reflux disease-related respiratory symptoms: a prospective 5-year study.Minerva Chir,69,293-299.
  6. Mattar, SG,Qureshi, F,Taylor, D(2006).Treatment of refractory gastroesophageal reflux disease with radiofrequency energy(Stretta) in patients after Roux-en-Y gastric bypass.Surg Endosc,20,850-854.
  7. McClusky, DA,Khaitan, L,Swafford, VA(2007).RF energy delivery to the LES(Stretta) in patients with recurrent reflux after antireflux surgery. Can surgery be avoided?.Surg Endosc,21,1207-1211.
  8. Noar, M,Squires, P,Khan, S(2017).Radiofrequency energy delivery to the lower esophageal sphincter improves gastroesophageal reflux patient-reported outcomes in failed laparoscopic Nissen fundoplication cohort.Surg Endosc,31,2854-2862.
  9. Noar, M,Squires, P,Noar, E(2014).Long-term maintenance effect of radiofrequency energy delivery for refractory GERD: a decade later.Surg Endosc,28,2323-2333.
  10. Noar, MD,Lotfi-Emran, S(2007).Gastrointest Endosc,65,367-372.
  11. Reymunde, A,Santiago, N(2007).Long-term results of radiofrequency energy delivery for the treatment of GERD: sustained improvements in symptoms, quality of life, and drug use at 4-year follow-up.Gastrointest Endosc,65,361-366.
  12. Alvaro Reymunde Fifteen Plus Years After Stretta Antireflux Endoscopy Procedure: Quality of Life and PPI Requirements 1354. https://eventscribe.com/2017/wcogacg2017/ajaxcalls/PosterInfo.asp?efp=S1lVTUxLQVozODMy&PosterID=114755&rnd=0.8574113
  13. Dimitrios Stefanidis, William Richardson, Briandunk in clinical spotlight review: endoluminal treatments for gastroesophageal reflux disease(gerd) 2018.