兒童多發性硬化症及其認知問題

10.6666/ClinMed.202110_88(4).0108

林為聖；林珊如

多發性硬化症（multiple sclerosis） ； 神經發炎（neuroinflammation） ； 認知（cognition） ； 認知復健（cognitive rehabilitation）

臨床醫學月刊

88卷4期（2021 / 10 / 29）

649 - 653

繁體中文

多發性硬化症是一種發生在中樞神經系統的慢性發炎性脫髓鞘疾病，其中約有3-10%是在成年之前發病，即所謂兒童多發性硬化症。這群病人在性別比、臨床表現與預後等方面均有別於成年發病的多發性硬化症患者。再者，兒童多發性硬化症雖然在發病後的頭10年內少見顯著的運動功能障礙，但有相當比例在病程早期即有認知功能異常，且可能隨病程進展而惡化。近年來國外漸有研究聚焦於此類病童的認知評估與介入。本文乃針對兒童多發性硬化症及其相伴的認知問題作一簡介。

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