题名

胸腔病例（三八五）小細胞肺癌合併異位性庫欣氏症

DOI

10.6666/ClinMed.202202_89(2).0022

作者

陳奕廷；江起陸

关键词

小細胞肺癌（small cell lung cancer） ； 異位性庫欣氏症（ectopic Cushing's syndrome） ； 腫瘤附屬症候群（paraneoplastic syndrome）

期刊名称

臨床醫學月刊

卷期/出版年月

89卷2期（2022 / 02 / 25）

页次

118 - 123

内容语文

繁體中文
中文摘要

異位性庫欣氏症（ectopic Cushing's syndrome, ECS）為小細胞肺癌第二常見（1-5%）的腫瘤附屬症候群（paraneoplastic syndrome）。而異位性庫欣氏症的病灶8-20%為小細胞肺癌，其次為肺類癌（carcinoid tumor）或胰臟、胸腺等部位的神經內分泌瘤。小細胞肺癌合併異位性庫欣氏症的預後表現不佳，對於化療治療的效果有限，感染與血栓栓塞的機會也較高。此類病人多以電解質不平衡與肌肉無力表現，較少能見月亮臉、軀幹型肥胖等典型庫欣氏症表現。除了腫瘤的治療以外，可用Etomidate、Fluconazole、Mifepristone等藥物治療高皮質醇血症（hypercortisolism）。
主题分类 醫藥衛生 > 基礎醫學
醫藥衛生 > 社會醫學
参考文献
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